Hs00820351_cn

• Gene Symbol: PIAS1
• Assay Reference Genome Location: Chr.15:68054352 on build GRCh38
• Cytoband: 15q23

Target Gene Details

• Entrez Gene ID: 8554
• Gene Name: protein inhibitor of activated STAT 1
• Gene Aliases: DDXBP1, GBP, GU/RH-II, ZMIZ3
• Location: Chr.15:68054179-68191464 on Build GRCh38
• Assay Gene Location: Overlaps Exon 1 - Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PIAS1	NM_016166.2			NP_057250.1
	AF077951.1			AAC36702.1
	AF167160.1			AAD49722.1
	AK314515.1
	AY826819.1
	BC118587.1
	BC121797.1
	EF487997.1
	EF487998.1
	FJ997900.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv517512	Chr.15:68026786 - 68132927 on Build GRCh38	Gain	PIAS1
nsv569803	Chr.15:67585107 - 68124237 on Build GRCh38	Gain	SKOR1 PIAS1 LOC101929076 MAP2K5 RNU6-1

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
JAK-STAT cascade
protein sumoylation
androgen receptor signaling pathway
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
positive regulation of protein sumoylation
regulation of cell proliferation
fat cell differentiation
positive regulation of transcription, DNA-templated
regulation of interferon-gamma-mediated signaling pathway

Function(s)

DNA binding
transcription coactivator activity
transcription corepressor activity
protein binding
transcription factor binding
zinc ion binding
ligase activity
SUMO transferase activity
enzyme binding
ubiquitin protein ligase binding
androgen receptor binding
SUMO ligase activity