Hs00793077_cn

• Gene Symbol: AICDA
• Assay Reference Genome Location: Chr.12:8606884 on build GRCh38
• Cytoband: 12p13.31

Target Gene Details

• Entrez Gene ID: 57379
• Gene Name: activation-induced cytidine deaminase
• Gene Aliases: AID, ARP2, CDA2, HEL-S-284, HIGM2
• Location: Chr.12:8602166-8612970 on Build GRCh38
• Assay Gene Location: Overlaps Intron 2 - Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
AICDA	NM_020661.2			NP_065712.1
	XM_011520772.2			XP_011519074.1
	XM_011520773.2			XP_011519075.1
	AB040431.1			BAB12721.1
	AF529815.1			AAM95402.1
	AF529816.1			AAM95403.1
	AF529817.1			AAM95404.1
	AF529818.1			AAM95405.1
	AF529819.1			AAM95406.1
	AF529820.1			AAM95407.1
	AF529821.1			AAM95408.1
	AF529822.1			AAM95409.1
	AF529823.1			AAM95410.1
	AF529824.1			AAM95411.1
	AF529825.1			AAM95412.1
	AF529826.1			AAM95413.1
	AF529827.1			AAM95414.1
	AY534975.1			AAS90604.1
	AY536516.1			AAS92920.1
	AY536517.1			AAS92921.1
	AY541058.1			AAS98257.1
	BC006296.2			AAH06296.1
	BT007402.1			AAP36066.1
	BX402063.2
	DQ431660.1
	EU794587.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1051530	Chr.12:8442286 - 9951690 on Build GRCh38	Gain	LINC00987 A2M LOC642846 LOC100506159 LOC400002 PZP CLEC2B A2MP1 KLRB1 LOC374443 OVOS KLRF2 CLECL1 KLRF1 MIR1244-3 RIMKLB CLEC4E CLEC2D LOC105376678 LOC728715 CLEC2A LOC105369649 KLRG1 LOC105369728 MFAP5 LOC101930452 M6PR DDX12P CD69 CLEC4D CLEC12A LOC101928030 A2ML1 AICDA A2M-AS1 LINC00612 PHC1 CLEC6A
nsv557342	Chr.12:8446801 - 8621931 on Build GRCh38	Loss	CLEC4E CLEC4D AICDA CLEC6A
dgv1362n100	Chr.12:8296504 - 8639973 on Build GRCh38	Gain	CLEC4E CLEC4D LINC00937 AICDA CLEC6A

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA processing factor

Gene Ontology Categories:

Process(es)

mRNA processing
cytidine deamination
somatic diversification of immunoglobulins
somatic hypermutation of immunoglobulin genes
B cell differentiation
isotype switching
cellular response to lipopolysaccharide
DNA demethylation
negative regulation of methylation-dependent chromatin silencing

Function(s)

cytidine deaminase activity
protein binding
zinc ion binding
ubiquitin protein ligase binding