Hs00699778_cn

• Gene Symbol: KLRG1
• Assay Reference Genome Location: Chr.12:9149617 on build GRCh38
• Cytoband: 12p13.31

Target Gene Details

• Entrez Gene ID: 10219
• Gene Name: killer cell lectin like receptor G1
• Gene Aliases: 2F1, CLEC15A, MAFA, MAFA-2F1, MAFA-L, MAFA-LIKE
• Location: Chr.12:8989079-9255692 on Build GRCh38
• Assay Gene Location: Within Intron 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
KLRG1	XM_017018685.1			XP_016874174.1

Target Gene Details

• Entrez Gene ID: 5858
• Gene Name: PZP, alpha-2-macroglobulin like
• Gene Aliases: CPAMD6
• Location: Chr.12:9140730-9208370 on Build GRCh38
• Assay Gene Location: Overlaps Intron 34 - Exon 35

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PZP	NM_002864.2			NP_002855.2
	XM_011520804.2			XP_011519106.1
	XM_011520805.2			XP_011519107.1
	XM_017019763.1			XP_016875252.1
	XM_017019764.1			XP_016875253.1
	XM_017019765.1			XP_016875254.1
	XM_017019766.1			XP_016875255.1
	AK313639.1
	BC111756.1			AAI11757.1
	X54380.1			CAA38255.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1051530	Chr.12:8442286 - 9951690 on Build GRCh38	Gain	RIMKLB KLRF1 M6PR A2M-AS1 LOC105376678 AICDA CLEC4E LOC101928030 CLEC2D CD69 CLEC2A LOC642846 MFAP5 A2ML1 MIR1244-3 OVOS LOC100506159 LOC101930452 LOC400002 LOC105369728 A2M LOC728715 A2MP1 LINC00612 PHC1 CLEC12A LOC105369649 DDX12P KLRG1 PZP CLEC6A CLEC2B KLRF2 CLECL1 KLRB1 LOC374443 LINC00987 CLEC4D
nsv527404	Chr.12:9098005 - 9282648 on Build GRCh38	Gain	A2MP1 MIR1244-3 KLRG1 LINC00987 PZP A2M

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor, protease inhibitor

Gene Ontology Categories:

Process(es)

inflammatory response
cellular defense response
cell surface receptor signaling pathway
innate immune response
female pregnancy
negative regulation of endopeptidase activity

Function(s)

receptor activity
protein binding
carbohydrate binding
endopeptidase inhibitor activity
serine-type endopeptidase inhibitor activity