Hs00678930_cn

• Gene Symbol: KLRG1
• Assay Reference Genome Location: Chr.12:9160014 on build GRCh38
• Cytoband: 12p13.31

Target Gene Details

• Entrez Gene ID: 10219
• Gene Name: killer cell lectin like receptor G1
• Gene Aliases: 2F1, CLEC15A, MAFA, MAFA-2F1, MAFA-L, MAFA-LIKE
• Location: Chr.12:8989079-9255692 on Build GRCh38
• Assay Gene Location: Within Intron 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
KLRG1	XM_017018685.1			XP_016874174.1

Target Gene Details

• Entrez Gene ID: 5858
• Gene Name: PZP, alpha-2-macroglobulin like
• Gene Aliases: CPAMD6
• Location: Chr.12:9140730-9208370 on Build GRCh38
• Assay Gene Location: Overlaps Intron 24 - Exon 25

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PZP	NM_002864.2			NP_002855.2
	XM_011520804.2			XP_011519106.1
	XM_011520805.2			XP_011519107.1
	XM_011520806.1			XP_011519108.1
	XM_017019763.1			XP_016875252.1
	XM_017019764.1			XP_016875253.1
	XM_017019765.1			XP_016875254.1
	XM_017019766.1			XP_016875255.1
	AK313639.1
	BC111756.1			AAI11757.1
	X54380.1			CAA38255.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv523958	Chr.12:9150844 - 9396476 on Build GRCh38	Loss	LINC00987 LOC101930452 LOC105369649 PZP MIR1244-3 LOC642846 KLRG1 LOC101928030 A2MP1
nsv1051530	Chr.12:8442286 - 9951690 on Build GRCh38	Gain	LOC101930452 A2ML1 KLRF1 LOC105376678 PZP CLECL1 LOC100506159 CLEC2B LOC105369728 KLRG1 LOC105369649 CLEC4D CLEC2D CD69 LOC642846 CLEC6A LOC101928030 A2MP1 LINC00987 KLRB1 CLEC4E LINC00612 LOC400002 MIR1244-3 CLEC2A LOC374443 AICDA LOC728715 DDX12P OVOS A2M-AS1 MFAP5 M6PR RIMKLB A2M KLRF2 PHC1 CLEC12A
nsv527404	Chr.12:9098005 - 9282648 on Build GRCh38	Gain	LINC00987 A2M PZP MIR1244-3 KLRG1 A2MP1
nsv557355	Chr.12:9157399 - 9376419 on Build GRCh38	Gain	LINC00987 LOC101930452 LOC105369649 PZP MIR1244-3 LOC642846 KLRG1 LOC101928030 A2MP1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor, protease inhibitor

Gene Ontology Categories:

Process(es)

inflammatory response
cellular defense response
cell surface receptor signaling pathway
innate immune response
female pregnancy
negative regulation of endopeptidase activity

Function(s)

receptor activity
protein binding
carbohydrate binding
endopeptidase inhibitor activity
serine-type endopeptidase inhibitor activity