Hs00628278_cn

• Gene Symbol: AICDA
• Assay Reference Genome Location: Chr.12:8604819 on build GRCh38
• Cytoband: 12p13.31

Target Gene Details

• Entrez Gene ID: 57379
• Gene Name: activation-induced cytidine deaminase
• Gene Aliases: AID, ARP2, CDA2, HEL-S-284, HIGM2
• Location: Chr.12:8602166-8612970 on Build GRCh38
• Assay Gene Location: Overlaps Intron 4 - Exon 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
AICDA	NM_020661.2			NP_065712.1
	XM_011520772.2			XP_011519074.1
	XM_011520773.2			XP_011519075.1
	AB040431.1			BAB12721.1
	AF529815.1			AAM95402.1
	AF529816.1			AAM95403.1
	AF529817.1			AAM95404.1
	AF529818.1			AAM95405.1
	AF529819.1			AAM95406.1
	AF529820.1			AAM95407.1
	AF529821.1			AAM95408.1
	AF529822.1			AAM95409.1
	AF529823.1			AAM95410.1
	AF529824.1			AAM95411.1
	AF529825.1			AAM95412.1
	AF529826.1			AAM95413.1
	AF529827.1			AAM95414.1
	AJ577811.1			CAE12261.1
	AY534975.1			AAS90604.1
	AY536516.1			AAS92920.1
	AY536517.1			AAS92921.1
	AY541058.1			AAS98257.1
	AY748364.1			AAU95780.1
	BC006296.2			AAH06296.1
	BT007402.1			AAP36066.1
	BX402063.2
	DQ431660.1
	EU794587.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv527782	Chr.12:8604195 - 8604885 on Build GRCh38	Gain	AICDA
nsv1051530	Chr.12:8442286 - 9951690 on Build GRCh38	Gain	LOC105369649 CLEC2D LOC100506159 KLRG1 KLRB1 PZP RIMKLB OVOS CLECL1 LOC101930452 M6PR LOC642846 KLRF1 DDX12P CLEC4D LINC00612 LOC105376678 LOC105369728 CLEC6A A2MP1 A2M PHC1 A2ML1 CD69 CLEC12A A2M-AS1 LOC728715 LOC400002 CLEC2A AICDA LOC374443 CLEC4E LOC101928030 MFAP5 CLEC2B MIR1244-3 LINC00987 KLRF2
nsv557342	Chr.12:8446801 - 8621931 on Build GRCh38	Loss	CLEC4E CLEC4D CLEC6A AICDA
dgv1362n100	Chr.12:8296504 - 8639973 on Build GRCh38	Gain	CLEC4E LINC00937 CLEC4D CLEC6A AICDA

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA processing factor

Gene Ontology Categories:

Process(es)

mRNA processing
cytidine deamination
somatic diversification of immunoglobulins
somatic hypermutation of immunoglobulin genes
B cell differentiation
isotype switching
cellular response to lipopolysaccharide
DNA demethylation
negative regulation of methylation-dependent chromatin silencing

Function(s)

cytidine deaminase activity
protein binding
zinc ion binding
ubiquitin protein ligase binding