Hs00561051_cn

• Gene Symbol: NOXO1
• Assay Reference Genome Location: Chr.16:1980572 on build GRCh38
• Cytoband: 16p13.3

Target Gene Details

• Entrez Gene ID: 124056
• Gene Name: NADPH oxidase organizer 1
• Gene Aliases: P41NOX, P41NOXA, P41NOXB, P41NOXC, SH3PXD5, SNX28
• Location: Chr.16:1978917-1982751 on Build GRCh38
• Assay Gene Location: Overlaps Intron 3 - Exon 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NOXO1	NM_001267721.1			NP_001254650.1
	NM_144603.3			NP_653204.1
	NM_172167.2			NP_751907.1
	NM_172168.2			NP_751908.1
	XM_005255099.4			XP_005255156.1
	XM_017022927.1			XP_016878416.1
	XM_017022928.1			XP_016878417.1
	AB097667.1			BAC76711.1
	AF532983.1			AAM97925.1
	AF532984.1			AAM97926.1
	AF532985.1			AAM97927.1
	AF539796.1			AAN75141.1
	AK292197.1
	AK310198.1	2	768
	AK313917.1
	AY191359.1			AAO38665.1
	AY255768.1			AAP13479.1
	BC015917.2			AAH15917.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2422427	Chr.16:10001 - 2723164 on Build GRCh38	Duplication	NPRL3 IGFALS MIR662 ZNF598 UBE2I SNHG19 PRSS29P TPSB2 TPSD1 PRSS27 MRPS34 FBXL16 NARFL PRR35 CASKIN1 WDR90 NME4 GFER MIR3180-5 MEIOB NUBP2 WDR24 NPW E4F1 MIR4717 SSTR5 POLR3K LINC00254 TSR3 ERVK13-1 RNF151 C16orf59 UNKL HAGHL MIR4516 MAPK8IP3 MSLN CHTF18 HBA2 LOC105371038 SNORA78 RGS11 LOC107984876 LOC105371184 RAB11FIP3 LOC105371045 METTL26 SYNGR3 HN1L TBL3 RNPS1 WFIKKN1 HAGH RHOT2 FAM173A RAB40C MIR3677 RPL3L SNORD60 NME3 HBA1 PRR25 C16orf91 LOC101929280 CCNF GNPTG CEMP1 TMEM204 DDX11L10 RPL23AP5 ATP6V0C PIGQ MIR3177 RHBDL1 BRICD5 DECR2 AMDHD2 IFT140 NOXO1 ECI1 MIR6768 SNORA10 JMJD8 MIR1225 AXIN1 HBZ LOC100134368 NTN3 FAM234A HBM LOC105371047 TSC2 MIR3176 DNASE1L2 BAIAP3 MIR5587 PDIA2 TMEM8A SLC9A3R2 CACNA1H MIR3178 CRAMP1 TPSG1 HS3ST6 RPS2 CCDC154 LOC652276 EME2 LINC00235 C1QTNF8 PGP ARHGDIG SNORA64 NTHL1 SSTR5-AS1 LUC7L PDPK1 MIR940 CLCN7 RHBDF1 WASIR2 RAB26 LOC105371046 MRPL28 MCRIP2 FLJ42627 TRAF7 PKD1 MIR6511B1 TELO2 LMF1-AS1 NDUFB10 LOC106660606 MIR6859-4 SNHG9 ABCA17P FAHD1 METRN PTX4 CAPN15 LOC107987233 MIR6767 LOC729652 SPSB3 SNRNP25 NHLRC4 GNG13 MPG SOX8 LMF1 LOC105371049 STUB1 TPSAB1 KCTD5 ABCA3 MSRB1 LOC100287175 TBC1D24 CCDC78 MLST8 HBQ1 RPUSD1
nsv521569	Chr.16:1971892 - 2035996 on Build GRCh38	Loss	NPW SLC9A3R2 ZNF598 SYNGR3 GFER TBL3 NOXO1
dgv4858n54	Chr.16:1955562 - 2038584 on Build GRCh38	Loss	NPW SLC9A3R2 SNORA10 ZNF598 SYNGR3 RPS2 TBL3 RNF151 NDUFB10 SNORA64 SNHG9 GFER NOXO1 SNORA78
nsv952901	Chr.16:1888800 - 2135899 on Build GRCh38	Deletion	NPW SLC9A3R2 SNORA10 MIR1225 ZNF598 HS3ST6 SYNGR3 RPS2 TBL3 RNF151 TSC2 PKD1 MIR6511B1 NDUFB10 LOC105371049 SNORA64 SNHG9 NTHL1 MSRB1 MIR4516 GFER NOXO1 SNORA78 RPL3L
nsv1160329	Chr.16:1961727 - 2128574 on Build GRCh38	Deletion	NPW SLC9A3R2 SNORA10 MIR1225 ZNF598 SYNGR3 RPS2 TBL3 RNF151 TSC2 PKD1 MIR6511B1 NDUFB10 LOC105371049 SNORA64 SNHG9 NTHL1 GFER NOXO1 SNORA78
dgv4860n54	Chr.16:1974897 - 1980689 on Build GRCh38	Loss	TBL3 NOXO1
nsv471070	Chr.16:1947613 - 2024218 on Build GRCh38	Gain	NPW SNORA10 ZNF598 SYNGR3 RPS2 TBL3 RNF151 NDUFB10 SNORA64 SNHG9 GFER NOXO1 SNORA78 RPL3L
nsv833120	Chr.16:1893102 - 1980660 on Build GRCh38	Loss	NDUFB10 SNORA10 SNORA64 SNHG9 MSRB1 HS3ST6 RPS2 TBL3 RNF151 NOXO1 SNORA78 RPL3L
dgv336n27	Chr.16:1965120 - 2038584 on Build GRCh38	Loss	NPW SLC9A3R2 SNHG9 ZNF598 SYNGR3 GFER TBL3 RNF151 NOXO1 SNORA78

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

superoxide metabolic process
regulation of hydrogen peroxide metabolic process
extracellular matrix disassembly
positive regulation of catalytic activity
oxidation-reduction process
regulation of respiratory burst

Function(s)

protein binding
phospholipid binding
superoxide-generating NADPH oxidase activator activity
enzyme binding
phosphatidylinositol binding
identical protein binding