Hs00202430_cn

• Gene Symbol: HELZ2
• Assay Reference Genome Location: Chr.20:63558090 on build GRCh38
• Cytoband: 20q13.33

Target Gene Details

• Entrez Gene ID: 85441
• Gene Name: helicase with zinc finger 2
• Gene Aliases: PDIP-1, PRIC285
• Location: Chr.20:63558086-63574239 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 20

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
HELZ2	NM_001037335.2			NP_001032412.2
	NM_033405.3			NP_208384.3
	AB051556.2
	AF517673.1			AAM74197.1
	AK074171.1			BAB84997.1
	BC150283.1
	BQ707207.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv953306	Chr.20:63151949 - 63571247 on Build GRCh38	Deletion	PPDPF ARFGAP1 MIR124-3 MIR3196 LOC107985425 CHRNA4 COL20A1 LOC100130587 HELZ2 LOC100130152 BIRC7 FNDC11 YTHDF1 FLJ16779 EEF1A2 LOC102723788 NKAIN4 PTK6 MIR4326 KCNQ2 SRMS
nsv586573	Chr.20:63535645 - 63560584 on Build GRCh38	Loss	PTK6 HELZ2 FNDC11 SRMS
nsv521734	Chr.20:63522433 - 63566995 on Build GRCh38	Loss	PTK6 HELZ2 FNDC11 SRMS
nsv9825	Chr.20:62775470 - 63601330 on Build GRCh38	Gain	ARFGAP1 MIR124-3 MIR3196 LOC107985425 DPH3P1 MRGBP CHRNA4 COL20A1 HELZ2 OGFR-AS1 BIRC7 YTHDF1 LINC01056 COL9A3 LINC00029 HAR1A FLJ16779 SLC17A9 EEF1A2 LOC102723788 LOC63930 PTK6 MIR4326 LINC00659 GMEB2 TCFL5 OGFR KCNQ2 SRMS PPDPF LOC107985428 HAR1B DIDO1 LOC100130587 LOC100130152 FNDC11 GID8 NKAIN4 BHLHE23
nsv470563	Chr.20:63486715 - 63793308 on Build GRCh38	Loss	ZGPAT PPDPF ZBTB46 LIME1 LOC100505771 RTEL1 HELZ2 FNDC11 SLC2A4RG STMN3 ARFRP1 EEF1A2 RTEL1-TNFRSF6B TNFRSF6B PTK6 GMEB2 SRMS
nsv834034	Chr.20:63462825 - 63625901 on Build GRCh38	Loss	PPDPF EEF1A2 PTK6 GMEB2 HELZ2 FNDC11 KCNQ2 SRMS
nsv517702	Chr.20:63540916 - 63581575 on Build GRCh38	Loss	HELZ2 FNDC11 SRMS
esv2758806	Chr.20:63470996 - 63745014 on Build GRCh38	Gain+Loss	ZGPAT PPDPF ZBTB46 LIME1 LOC100505771 RTEL1 HELZ2 FNDC11 SLC2A4RG STMN3 ARFRP1 EEF1A2 RTEL1-TNFRSF6B TNFRSF6B PTK6 GMEB2 KCNQ2 SRMS

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Process(es)

transcription, DNA-templated
cellular lipid metabolic process
positive regulation of transcription from RNA polymerase II promoter

Function(s)

DNA binding
helicase activity
protein binding
ATP binding
ligand-dependent nuclear receptor transcription coactivator activity
poly(A) RNA binding
metal ion binding