Hs00201440_cn

• Gene Symbol: SEMA4C
• Assay Reference Genome Location: Chr.2:96864744 on build GRCh38
• Cytoband: 2q11.2

Target Gene Details

• Entrez Gene ID: 54910
• Gene Name: semaphorin 4C
• Gene Aliases: M-SEMA-F, SEMACL1, SEMAF, SEMAI
• Location: Chr.2:96859736-96870943 on Build GRCh38
• Assay Gene Location: Overlaps Intron 11 - Exon 11

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SEMA4C	NM_017789.4			NP_060259.4
	XM_006712606.3			XP_006712669.2
	XM_011511378.2			XP_011509680.1
	XM_011511379.2			XP_011509681.1
	XM_011511380.1			XP_011509682.1
	XM_011511381.1			XP_011509683.1
	XM_011511382.2			XP_011509684.1
	XM_011511383.1			XP_011509685.1
	XM_017004393.1			XP_016859882.1
	XM_017004394.1			XP_016859883.1
	AB051526.1			BAB21830.1
	AK000376.1			BAA91124.1
	AY358842.1			AAQ89201.1
	BC017476.1			AAH17476.2
	BC062984.1			AAH62984.1
	BC109103.1			AAI09104.1
	BC109104.1			AAI09105.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv526313	Chr.2:96667755 - 96994882 on Build GRCh38	Loss	MIR3127 ANKRD23 SEMA4C LMAN2L CNNM3 ANKRD39 LOC101927053 CNNM4 FER1L5 FAM178B
dgv607e201	Chr.2:95855884 - 97561622 on Build GRCh38	Deletion	MIR3127 SEMA4C NEURL3 CIAO1 ITPRIPL1 LOC101927053 FER1L5 ANKRD36B ANKRD36C LMAN2L ANKRD36 ARID5A KANSL3 ANKRD39 LOC105373495 CNNM4 NCAPH ASTL LOC100506076 ANKRD23 DUSP2 STARD7-AS1 CNNM3 FAHD2B GPAT2 TMEM127 SNRNP200 LOC100506123 LOC653924 LOC107984110 FAHD2CP LOC105373496 STARD7 ADRA2B FAM178B
nsv1135873	Chr.2:95981454 - 97579645 on Build GRCh38	Deletion	MIR3127 SEMA4C NEURL3 CIAO1 ITPRIPL1 LOC101927053 FER1L5 ANKRD36B ANKRD36C LMAN2L ANKRD36 ARID5A KANSL3 ANKRD39 LOC105373495 CNNM4 NCAPH ASTL LOC100506076 ANKRD23 DUSP2 STARD7-AS1 CNNM3 FAHD2B GPAT2 TMEM127 SNRNP200 LOC100506123 LOC653924 LOC107984110 FAHD2CP LOC105373496 STARD7 ADRA2B FAM178B
esv3425717	Chr.2:95859900 - 97515905 on Build GRCh38	Duplication	MIR3127 SEMA4C NEURL3 CIAO1 ITPRIPL1 LOC101927053 FER1L5 ANKRD36B ANKRD36C LMAN2L ANKRD36 ARID5A KANSL3 ANKRD39 LOC105373495 CNNM4 NCAPH ASTL LOC100506076 ANKRD23 DUSP2 STARD7-AS1 CNNM3 FAHD2B GPAT2 TMEM127 SNRNP200 LOC100506123 LOC653924 LOC107984110 FAHD2CP LOC105373496 STARD7 ADRA2B FAM178B

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

membrane-bound signaling molecule, intercellular signal molecule

Gene Ontology Categories:

Process(es)

neural crest cell migration
neural tube closure
cell migration in hindbrain
cerebellum development
positive regulation of cell migration
positive regulation of stress-activated MAPK cascade
muscle cell differentiation
negative regulation of axon extension involved in axon guidance
negative chemotaxis
semaphorin-plexin signaling pathway

Function(s)

protein binding
semaphorin receptor binding
neuropilin binding
chemorepellent activity