Mm00533869_cn

• Gene Symbol: Ptprc
• Assay Reference Genome Location: Chr.1:138063176 on build GRCm38
• Cytoband: 1E4

Target Gene Details

• Entrez Gene ID: 19264
• Gene Name: protein tyrosine phosphatase, receptor type, C
• Gene Aliases: B220, CD45R, Cd45, L-CA, Ly-5, Lyt-4, T200, loc
• Location: Chr.1:138062859-138175755 on Build GRCm38
• Assay Gene Location: Within Exon 33

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Ptprc	NM_001111316.2	32	5251	NP_001104786.2
	NM_001268286.1	29	4860	NP_001255215.1
	NM_011210.4	30	4932	NP_035340.3
	AK079399.1	1	1035
	BM239381.2	1	318

More Information

• Set Membership: Intragenic, Exonic

Panther Classification:

Molecular Function -

protein phosphatase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

activation of MAPK activity
negative regulation of T cell mediated cytotoxicity
positive regulation of T cell mediated cytotoxicity
negative regulation of cytokine-mediated signaling pathway
hematopoietic progenitor cell differentiation
immunoglobulin biosynthetic process
positive regulation of T cell mediated immunity
regulation of humoral immune response mediated by circulating immunoglobulin
positive regulation of humoral immune response mediated by circulating immunoglobulin
negative regulation of protein kinase activity
protein dephosphorylation
negative regulation of cell adhesion involved in substrate-bound cell migration
leukocyte cell-cell adhesion
response to gamma radiation
dephosphorylation
B cell differentiation
T cell differentiation
positive regulation of B cell proliferation
negative regulation of protein autophosphorylation
heterotypic cell-cell adhesion
peptidyl-tyrosine dephosphorylation
T cell proliferation
B cell proliferation
positive regulation of T cell proliferation
positive regulation of MAPK cascade
cell cycle phase transition
positive thymic T cell selection
negative thymic T cell selection
regulation of B cell differentiation
positive regulation of T cell differentiation
positive regulation of gamma-delta T cell differentiation
positive regulation of alpha-beta T cell proliferation
positive regulation of isotype switching to IgG isotypes
bone marrow development
stem cell development
negative regulation of peptidyl-tyrosine phosphorylation
T cell receptor signaling pathway
B cell receptor signaling pathway
regulation of B cell receptor signaling pathway
positive regulation of antigen receptor-mediated signaling pathway
release of sequestered calcium ion into cytosol
defense response to virus
regulation of cell cycle
positive regulation of hematopoietic stem cell migration
positive regulation of stem cell proliferation
regulation of extrinsic apoptotic signaling pathway
positive regulation of extrinsic apoptotic signaling pathway

Function(s)

phosphoprotein phosphatase activity
protein tyrosine phosphatase activity
protein binding
heparin binding
hydrolase activity
phosphatase activity
protein kinase binding
heparan sulfate proteoglycan binding