Mm00434904_cn

• Gene Symbol: Srebf2
• Assay Reference Genome Location: Chr.15:82177578 on build GRCm38
• Cytoband: 15E1

Target Gene Details

• Entrez Gene ID: 20788
• Gene Name: sterol regulatory element binding factor 2
• Gene Aliases: AI608257, SREBP-2, SREBP2, SREBP2gc, bHLHd2, lop13, nuc
• Location: Chr.15:82147269-82205379 on Build GRCm38
• Assay Gene Location: Overlaps Exon 7 - Intron 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Srebf2	NM_033218.1			NP_150087.1
	AF289715.2			AAG01859.2
	AF374267.1			AAK54763.1
	AK155857.1			BAE33463.1
	AK172219.1

More Information

• Set Membership: Intragenic, Non-exonic

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
lipid metabolic process
steroid metabolic process
cholesterol metabolic process
cellular response to starvation
response to hormone
positive regulation of cholesterol storage
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter
negative regulation of cholesterol efflux
regulation of mitophagy
positive regulation of protein targeting to mitochondrion
regulation of cholesterol homeostasis

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
protein C-terminus binding
sequence-specific DNA binding
transcription regulatory region DNA binding
protein dimerization activity
E-box binding