Mm00000517_cn

• Gene Symbol: Il2
• Assay Reference Genome Location: Chr.3:37123171 on build GRCm38
• Cytoband: 3B

Target Gene Details

• Entrez Gene ID: 16183
• Gene Name: interleukin 2
• Gene Aliases: Il-2
• Location: Chr.3:37120713-37125954 on Build GRCm38
• Assay Gene Location: Overlaps Intron 2 - Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Il2	NM_008366.3			NP_032392.1
	AF065914.1			AAD25890.1
	AF065915.1			AAD25891.1
	AF065916.1			AAD25892.1
	AY147902.1			AAN38301.1
	BC116845.1
	BC116873.1
	DQ836354.1
	K02292.1			AAA39289.1
	U41494.1			AAB39206.1
	U41504.1			AAB39208.1
	U41505.1			AAB39209.1
	U41506.1			AAB39210.1
	X01772.1			CAA25909.1
	X73040.1

More Information

• Set Membership: Intragenic, Non-exonic

Panther Classification:

Molecular Function -

actin or actin-binding cytoskeletal protein, non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

negative regulation of protein phosphorylation
positive regulation of protein phosphorylation
immune system process
negative regulation of B cell apoptotic process
immune response
G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
protein kinase C-activating G-protein coupled receptor signaling pathway
positive regulation of B cell proliferation
positive regulation of interferon-gamma production
positive regulation of interleukin-17 production
positive regulation of T cell proliferation
positive regulation of activated T cell proliferation
positive regulation of tyrosine phosphorylation of Stat5 protein
positive regulation of T cell differentiation
positive regulation of regulatory T cell differentiation
negative regulation of heart contraction
positive regulation of transcription from RNA polymerase II promoter
regulation of T cell homeostatic proliferation
positive regulation of isotype switching to IgG isotypes
negative regulation of lymphocyte proliferation
negative regulation of inflammatory response
positive regulation of immunoglobulin secretion
positive regulation of dendritic spine development
extrinsic apoptotic signaling pathway in absence of ligand

Function(s)

cytokine activity
interleukin-2 receptor binding
growth factor activity
carbohydrate binding
kappa-type opioid receptor binding
glycosphingolipid binding