Hs06951177_cn

• Gene Symbol: CHD4
• Assay Reference Genome Location: Chr.12:6587089 on build GRCh38
• Cytoband: 12p13.31

Target Gene Details

• Entrez Gene ID: 1108
• Gene Name: chromodomain helicase DNA binding protein 4
• Gene Aliases: CHD-4, Mi-2b, Mi2-BETA
• Location: Chr.12:6570082-6607439 on Build GRCh38
• Assay Gene Location: Within Intron 25

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CHD4	NM_001273.3			NP_001264.2
	NM_001297553.1			NP_001284482.1
	XM_005253668.3			XP_005253725.1
	XM_006718958.1			XP_006719021.1
	XM_006718959.1			XP_006719022.1
	XM_006718960.1			XP_006719023.1
	XM_006718961.2			XP_006719024.1
	XM_006718962.1			XP_006719025.1
	XM_017018725.1			XP_016874214.1
	XM_017018726.1			XP_016874215.1
	XM_017018727.1			XP_016874216.1
	XM_017018728.1			XP_016874217.1
	XM_017018729.1			XP_016874218.1
	XM_017018730.1			XP_016874219.1
	XM_017018731.1			XP_016874220.1
	XM_017018732.1			XP_016874221.1
	XM_017018733.1			XP_016874222.1
	XM_017018734.1			XP_016874223.1
	AK128741.1
	BC038596.1			AAH38596.1
	CR936680.1
	X86691.1			CAA60384.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv509452	Chr.12:6566935 - 6653627 on Build GRCh38	Insertion	SCARNA11 NOP2 ING4 ACRBP LPAR5 CHD4
nsv826210	Chr.12:6561863 - 6612310 on Build GRCh38	Gain	SCARNA11 NOP2 CHD4
nsv973982	Chr.12:6578894 - 6587817 on Build GRCh38	Duplication	SCARNA11 CHD4
nsv832322	Chr.12:6575884 - 6765914 on Build GRCh38	Loss	SCARNA11 COPS7A ING4 ACRBP PIANP LPAR5 CHD4 ZNF384 MLF2
nsv826211	Chr.12:6578422 - 6592697 on Build GRCh38	Gain	SCARNA11 CHD4

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
histone deacetylation
DNA duplex unwinding
ATP-dependent chromatin remodeling
spindle assembly
terminal button organization
regulation of signal transduction by p53 class mediator

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
RNA polymerase II repressing transcription factor binding
DNA binding
ATP-dependent DNA helicase activity
histone deacetylase activity
protein binding
ATP binding
microtubule binding
zinc ion binding
nucleosomal DNA binding