Hs06654446_cn

• Gene Symbol: PPM1L
• Assay Reference Genome Location: Chr.3:160781605 on build GRCh38
• Cytoband: 3q25.33

Target Gene Details

• Entrez Gene ID: 151742
• Gene Name: protein phosphatase, Mg2+/Mn2+ dependent 1L
• Gene Aliases: PP2C-epsilon, PP2CE, PPM1-LIKE
• Location: Chr.3:160755532-161078907 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PPM1L	NM_139245.3			NP_640338.2
	XM_011512440.2			XP_011510742.1
	AY337264.1			AAR00269.1
	DB032505.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3598389	Chr.3:160767086 - 160857900 on Build GRCh38	Loss	PPM1L
esv3598390	Chr.3:160768581 - 160829645 on Build GRCh38	Loss	PPM1L

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protein phosphatase

Gene Ontology Categories:

Process(es)

MAPK cascade
protein dephosphorylation
transmembrane receptor protein serine/threonine kinase signaling pathway
sphingolipid biosynthetic process

Function(s)

protein serine/threonine phosphatase activity
metal ion binding