Hs06641318_cn

• Gene Symbol: NLGN1
• Assay Reference Genome Location: Chr.3:173403570 on build GRCh38
• Cytoband: 3q26.31

Target Gene Details

• Entrez Gene ID: 22871
• Gene Name: neuroligin 1
• Gene Aliases: NL1
• Location: Chr.3:173395899-174291287 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NLGN1	NM_014932.3			NP_055747.1
	XM_005247234.2			XP_005247291.1
	XM_005247236.2			XP_005247293.1
	XM_011512551.2			XP_011510853.1
	XM_011512552.2			XP_011510854.1
	XM_017005888.1			XP_016861377.1
	XM_017005889.1			XP_016861378.1
	XM_017005890.1			XP_016861379.1
	XM_017005892.1			XP_016861381.1
	XM_017005893.1			XP_016861382.1
	XM_017005896.1			XP_016861385.1
	XM_017005897.1			XP_016861386.1
	XM_017005898.1			XP_016861387.1
	XM_017005899.1			XP_016861388.1
	XM_017005900.1			XP_016861389.1
	XM_017005901.1			XP_016861390.1
	XM_017005902.1			XP_016861391.1
	XM_017005904.1			XP_016861393.1
	BC032555.1			AAH32555.1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, non-DGV Variation

Panther Classification:

Molecular Function -

cell adhesion molecule

Gene Ontology Categories:

Process(es)

regulation of respiratory gaseous exchange by neurological system process
protein targeting
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
neuron cell-cell adhesion
nervous system development
synapse assembly
positive regulation of circadian sleep/wake cycle, wakefulness
synaptic vesicle targeting
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
neuronal signal transduction
neuron projection development
positive regulation of synaptic transmission, GABAergic
protein localization to synapse
establishment of protein localization
regulation of neuron differentiation
rhythmic process
cytoskeletal matrix organization at active zone
protein homooligomerization
protein heterotetramerization
positive regulation of filopodium assembly
positive regulation of synapse assembly
positive regulation of synaptic transmission, glutamatergic
long-term synaptic potentiation
positive regulation of dendritic spine development
negative regulation of dendritic spine morphogenesis
terminal button organization
synaptic vesicle clustering
postsynaptic membrane assembly
presynaptic membrane assembly
AMPA glutamate receptor clustering
NMDA glutamate receptor clustering
neurexin clustering involved in presynaptic membrane assembly
postsynaptic density protein 95 clustering
receptor localization to synapse
positive regulation of ruffle assembly
positive regulation of synaptic vesicle endocytosis
positive regulation of protein localization to synapse
positive regulation of intracellular signal transduction
positive regulation of synaptic vesicle exocytosis
regulation of N-methyl-D-aspartate selective glutamate receptor activity
regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
positive regulation of excitatory postsynaptic potential
positive regulation of synaptic vesicle clustering

Function(s)

receptor activity
PDZ domain binding
neurexin family protein binding
protein dimerization activity
cell adhesion molecule binding
carboxylic ester hydrolase activity
scaffold protein binding