Hs06548165_cn

• Gene Symbol: SMYD3
• Assay Reference Genome Location: Chr.1:245767798 on build GRCh38
• Cytoband: 1q44

Target Gene Details

• Entrez Gene ID: 64754
• Gene Name: SET and MYND domain containing 3
• Gene Aliases: KMT3E, ZMYND1, ZNFN3A1, bA74P14.1
• Location: Chr.1:245749340-246507342 on Build GRCh38
• Assay Gene Location: Within Intron 20

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SMYD3	NM_001167740.1			NP_001161212.1
	NM_022743.2			NP_073580.1
	XM_011544253.1			XP_011542555.1
	XM_011544254.2			XP_011542556.1
	XM_011544257.1			XP_011542559.1
	XM_011544258.2			XP_011542560.1
	XM_011544259.2			XP_011542561.1
	XM_011544260.1			XP_011542562.1
	XM_011544261.2			XP_011542563.1
	XM_017002094.1			XP_016857583.1
	XM_017002095.1			XP_016857584.1
	AB057595.1			BAB86333.1
	AK023594.1
	AK024733.1			BAB14981.1
	AK289605.1
	AW173130.1
	AY186742.1			AAO31695.1
	BC017079.1			AAH17079.2
	BC031010.1			AAH31010.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3589447	Chr.1:245767201 - 245780520 on Build GRCh38	Loss	SMYD3
esv3891326	Chr.1:245759378 - 245988873 on Build GRCh38	Gain	SMYD3
esv3575839	Chr.1:245526258 - 245999859 on Build GRCh38	Gain	SMYD3 KIF26B
nsv549520	Chr.1:245750982 - 245836536 on Build GRCh38	Gain	SMYD3
nsv998007	Chr.1:245721457 - 245826060 on Build GRCh38	Loss	SMYD3

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

histone modifying enzyme

Gene Ontology Categories:

Process(es)

nucleosome assembly
negative regulation of protein kinase activity
myotube cell development
positive regulation of peptidyl-serine phosphorylation
histone lysine methylation
establishment of protein localization
positive regulation of transcription from RNA polymerase II promoter
cellular response to dexamethasone stimulus

Function(s)

RNA polymerase II core promoter sequence-specific DNA binding
RNA polymerase II core binding
RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding
histone-lysine N-methyltransferase activity
metal ion binding