Hs06085199_cn

• Gene Symbol: CCNB1
• Assay Reference Genome Location: Chr.5:69169428 on build GRCh38
• Cytoband: 5q13.2

Target Gene Details

• Entrez Gene ID: 891
• Gene Name: cyclin B1
• Gene Aliases: CCNB
• Location: Chr.5:69167010-69178245 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CCNB1	NM_031966.3			NP_114172.1
	AK289431.1
	AM851053.1
	BC006510.2			AAH06510.1
	BI253686.1
	BT020128.1			AAV38930.1
	M25753.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv5694n100	Chr.5:69081291 - 69374274 on Build GRCh38	Gain	TAF9 AK6 CDK7 CCDC125 CENPH SLC30A5 RAD17 CCNB1 MRPS36
nsv509066	Chr.5:69168549 - 69226419 on Build GRCh38	Insertion	CENPH CCNB1 MRPS36

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

kinase activator

Gene Ontology Categories:

Process(es)

G2/M transition of mitotic cell cycle
oocyte maturation
in utero embryonic development
negative regulation of protein phosphorylation
protein complex assembly
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
mitotic spindle organization
mitotic nuclear envelope disassembly
mitotic metaphase plate congression
spermatogenesis
response to mechanical stimulus
negative regulation of gene expression
anaphase-promoting complex-dependent catabolic process
positive regulation of mRNA 3'-end processing
positive regulation of histone phosphorylation
tissue regeneration
response to drug
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
positive regulation of mitotic cell cycle
response to DDT
positive regulation of fibroblast proliferation
digestive tract development
cell division
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
regulation of cell cycle
positive regulation of attachment of spindle microtubules to kinetochore
ventricular cardiac muscle cell development
positive regulation of cardiac muscle cell proliferation
regulation of chromosome condensation
cellular response to iron(III) ion
cellular response to fatty acid
cellular response to organic cyclic compound
cellular response to hypoxia
regulation of mitotic cell cycle spindle assembly checkpoint
histone H3-S10 phosphorylation involved in chromosome condensation

Function(s)

cyclin-dependent protein serine/threonine kinase activity
patched binding
protein binding
protein kinase binding
histone kinase activity