Hs05848480_cn

• Gene Symbol: IL1RL1
• Assay Reference Genome Location: Chr.2:102320225 on build GRCh38
• Cytoband: 2q12.1

Target Gene Details

• Entrez Gene ID: 9173
• Gene Name: interleukin 1 receptor like 1
• Gene Aliases: DER4, FIT-1, IL33R, ST2, ST2L, ST2V, T1
• Location: Chr.2:102311502-102352367 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
IL1RL1	NM_001282408.1			NP_001269337.1
	NM_016232.4			NP_057316.3
	XM_011512151.1			XP_011510453.1
	AB012701.3
	AK303389.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2673990	Chr.2:102314830 - 102320561 on Build GRCh38	Deletion	IL1RL1
esv3591787	Chr.2:102314919 - 102320486 on Build GRCh38	Loss	IL1RL1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

negative regulation of T-helper 1 type immune response
immune response
signal transduction
negative regulation of cell proliferation
negative regulation of interferon-gamma production
positive regulation of interleukin-5 production
interleukin-33-mediated signaling pathway
positive regulation of macrophage activation
negative regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of inflammatory response
positive regulation of chemokine secretion
cellular response to peptide

Function(s)

interleukin-33 binding
interleukin-33 receptor activity
cytokine receptor activity
interleukin-1 receptor activity
receptor signaling protein activity
protein binding