Hs05413045_cn

• Gene Symbol: CDH1
• Assay Reference Genome Location: Chr.16:68738044 on build GRCh38
• Cytoband: 16q22.1

Target Gene Details

• Entrez Gene ID: 999
• Gene Name: cadherin 1
• Gene Aliases: Arc-1, CD324, CDHE, ECAD, LCAM, UVO
• Location: Chr.16:68737290-68835542 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CDH1	NM_001317184.1			NP_001304113.1
	NM_001317185.1			NP_001304114.1
	NM_001317186.1			NP_001304115.1
	NM_004360.4			NP_004351.1
	AB025105.1			BAA88956.1
	AB025106.1			BAA88957.1
	AK290012.1
	AK297913.1
	AK312551.1
	BC141838.1
	BC146662.1
	EU709494.1
	L08599.1			AAA61259.1
	Z13009.1			CAA78353.1
	Z18923.1			CAA79356.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833267	Chr.16:68648596 - 68823901 on Build GRCh38	Gain	CDH3 CDH1
nsv457515	Chr.16:68564104 - 68890598 on Build GRCh38	Gain	CDH3 TANGO6 CDH1 ZFP90

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

cadherin

Gene Ontology Categories:

Process(es)

homophilic cell adhesion via plasma membrane adhesion molecules
synapse assembly
response to toxic substance
single organismal cell-cell adhesion
pituitary gland development
negative regulation of cell-cell adhesion
extracellular matrix disassembly
extracellular matrix organization
neuron projection development
adherens junction organization
response to drug
positive regulation of transcription factor import into nucleus
positive regulation of transcription, DNA-templated
cellular response to lithium ion
cellular response to indole-3-methanol
protein localization to plasma membrane
establishment of protein localization to plasma membrane

Function(s)

glycoprotein binding
calcium ion binding
protein binding
beta-catenin binding
ankyrin binding
GTPase activating protein binding
gamma-catenin binding
cell adhesion molecule binding
cadherin binding involved in cell-cell adhesion