Hs05381981_cn

• Gene Symbol: BCL2L10
• Assay Reference Genome Location: Chr.15:52110903 on build GRCh38
• Cytoband: 15q21.2

Target Gene Details

• Entrez Gene ID: 10017
• Gene Name: BCL2 like 10
• Gene Aliases: BCL-B, Boo, Diva, bcl2-L-10
• Location: Chr.15:52109263-52112775 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
BCL2L10	NM_001306168.1			NP_001293097.1
	NM_020396.3			NP_065129.1
	AF285092.1			AAG00503.1
	AF326964.1			AAK48715.1
	BC093826.1			AAH93826.1
	BC093828.1			AAH93828.1
	BC104442.1			AAI04443.1
	BC104443.1			AAI04444.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv952627	Chr.15:52110004 - 52113203 on Build GRCh38	Deletion	BCL2L10
nsv471244	Chr.15:52013266 - 52219268 on Build GRCh38	Gain	LOC100129973 GNB5 MYO5C BCL2L10 MAPK6
nsv833005	Chr.15:52097672 - 52249133 on Build GRCh38	Gain	LOC100129973 GNB5 MYO5C BCL2L10

More Information

Additional Information:

For this assay, SNP(s) [rs77272195] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

activation of cysteine-type endopeptidase activity involved in apoptotic process
spermatogenesis
female gamete generation
intrinsic apoptotic signaling pathway in response to DNA damage
negative regulation of apoptotic process
extrinsic apoptotic signaling pathway in absence of ligand
negative regulation of intrinsic apoptotic signaling pathway

Function(s)

protein binding
protein homodimerization activity
protein heterodimerization activity