Hs04607141_cn

• Gene Symbol: SEMA4C
• Assay Reference Genome Location: Chr.2:96868652 on build GRCh38
• Cytoband: 2q11.2

Target Gene Details

• Entrez Gene ID: 54910
• Gene Name: semaphorin 4C
• Gene Aliases: M-SEMA-F, SEMACL1, SEMAF, SEMAI
• Location: Chr.2:96859736-96870943 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SEMA4C	NM_017789.4			NP_060259.4
	XM_006712606.3			XP_006712669.2
	XM_011511378.2			XP_011509680.1
	XM_011511379.2			XP_011509681.1
	XM_011511380.1			XP_011509682.1
	XM_011511381.1			XP_011509683.1
	AY358842.1			AAQ89201.1
	BC109103.1			AAI09104.1
	BC109104.1			AAI09105.1
	BI518922.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv526313	Chr.2:96667755 - 96994882 on Build GRCh38	Loss	CNNM4 SEMA4C MIR3127 FER1L5 FAM178B ANKRD39 LMAN2L ANKRD23 CNNM3 LOC101927053
dgv607e201	Chr.2:95855884 - 97561622 on Build GRCh38	Deletion	CNNM4 LOC107984110 FER1L5 NCAPH LOC100506123 CNNM3 KANSL3 TMEM127 MIR3127 ARID5A FAHD2CP LMAN2L LOC100506076 ITPRIPL1 ANKRD36C STARD7-AS1 GPAT2 SEMA4C LOC105373496 FAM178B ADRA2B LOC653924 STARD7 ASTL ANKRD36 CIAO1 ANKRD39 LOC105373495 NEURL3 ANKRD36B SNRNP200 DUSP2 ANKRD23 FAHD2B LOC101927053
nsv1135873	Chr.2:95981454 - 97579645 on Build GRCh38	Deletion	CNNM4 LOC107984110 FER1L5 NCAPH LOC100506123 CNNM3 KANSL3 TMEM127 MIR3127 ARID5A FAHD2CP LMAN2L LOC100506076 ITPRIPL1 ANKRD36C STARD7-AS1 GPAT2 SEMA4C LOC105373496 FAM178B ADRA2B LOC653924 STARD7 ASTL ANKRD36 CIAO1 ANKRD39 LOC105373495 NEURL3 ANKRD36B SNRNP200 DUSP2 ANKRD23 FAHD2B LOC101927053
esv3425717	Chr.2:95859900 - 97515905 on Build GRCh38	Duplication	CNNM4 LOC107984110 FER1L5 NCAPH LOC100506123 CNNM3 KANSL3 TMEM127 MIR3127 ARID5A FAHD2CP LMAN2L LOC100506076 ITPRIPL1 ANKRD36C STARD7-AS1 GPAT2 SEMA4C LOC105373496 FAM178B ADRA2B LOC653924 STARD7 ASTL ANKRD36 CIAO1 ANKRD39 LOC105373495 NEURL3 ANKRD36B SNRNP200 DUSP2 ANKRD23 FAHD2B LOC101927053

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

membrane-bound signaling molecule, intercellular signal molecule

Gene Ontology Categories:

Process(es)

neural crest cell migration
neural tube closure
cell migration in hindbrain
cerebellum development
positive regulation of cell migration
positive regulation of stress-activated MAPK cascade
muscle cell differentiation
negative regulation of axon extension involved in axon guidance
negative chemotaxis
semaphorin-plexin signaling pathway

Function(s)

protein binding
semaphorin receptor binding
neuropilin binding
chemorepellent activity