Hs04351495_cn

• Gene Symbol: BOP1
• Assay Reference Genome Location: Chr.8:144283730 on build GRCh38
• Cytoband: 8q24.3

Target Gene Details

• Entrez Gene ID: 23246
• Gene Name: block of proliferation 1
• Gene Aliases: -
• Location: Chr.8:144262046-144291438 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
BOP1	NM_015201.4			NP_056016.1
	AB060694.1			BAB70666.1
	AK024840.1
	AK290677.1
	AK293719.1
	AK315612.1
	BC001086.2			AAH01086.2
	BC005160.2			AAH05160.2
	BC007274.1			AAH07274.1
	BC013787.1			AAH13787.1
	BC013980.2			AAH13980.1
	BC017674.2			AAH17674.1
	BQ711345.1
	D50914.1			BAA09473.1
	DA510177.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv12434n54	Chr.8:144270080 - 144516801 on Build GRCh38	Loss	TONSL-AS1 MIR6849 SLC52A2 FOXH1 HSF1 MIR1234 MFSD3 BOP1 SCRT1 MIR6848 PPP1R16A FBXL6 MIR6893 CPSF1 LOC101928902 DGAT1 VPS28 KIFC2 RECQL4 TONSL TMEM249 CYHR1 GPT SLC39A4 MIR939 ADCK5 LOC101928953
nsv470249	Chr.8:143889098 - 144519234 on Build GRCh38	Loss	MIR661 TONSL-AS1 MIR6849 WDR97 SLC52A2 OPLAH FOXH1 HSF1 MIR1234 MFSD3 BOP1 SCRT1 LRRC14 CYC1 MIR6848 PPP1R16A FBXL6 GRINA MIR6847 MIR6893 CPSF1 LOC101928902 DGAT1 VPS28 PLEC SMPD5 HGH1 KIFC2 MROH1 RECQL4 SCX SPATC1 TONSL TMEM249 CYHR1 MIR6846 MAF1 GPT MIR7112 SLC39A4 GPAA1 MIR939 PARP10 ADCK5 EXOSC4 LOC101928953 SHARPIN
nsv515809	Chr.8:143904439 - 144519234 on Build GRCh38	Gain+Loss	MIR661 TONSL-AS1 MIR6849 WDR97 SLC52A2 OPLAH FOXH1 HSF1 MIR1234 MFSD3 BOP1 SCRT1 LRRC14 CYC1 MIR6848 PPP1R16A FBXL6 GRINA MIR6847 MIR6893 CPSF1 LOC101928902 DGAT1 VPS28 PLEC SMPD5 HGH1 KIFC2 MROH1 RECQL4 SCX SPATC1 TONSL TMEM249 CYHR1 MIR6846 MAF1 GPT MIR7112 SLC39A4 GPAA1 MIR939 PARP10 ADCK5 EXOSC4 LOC101928953 SHARPIN
nsv1025071	Chr.8:144044224 - 144300847 on Build GRCh38	Gain	SMPD5 HGH1 MROH1 WDR97 OPLAH HSF1 SCX SPATC1 BOP1 CYC1 MIR6846 MAF1 MIR7112 MIR6847 GPAA1 EXOSC4 SHARPIN
nsv428208	Chr.8:144041826 - 144722291 on Build GRCh38	Gain	TONSL-AS1 MIR6849 WDR97 SLC52A2 OPLAH FOXH1 HSF1 MIR1234 MFSD3 LRRC24 BOP1 SCRT1 LRRC14 CYC1 MIR6848 PPP1R16A FBXL6 ZNF251 MIR6847 MIR6893 CPSF1 LOC101928902 DGAT1 VPS28 SMPD5 HGH1 KIFC2 MROH1 RECQL4 SCX SPATC1 TONSL TMEM249 CYHR1 MIR6846 MAF1 GPT MIR7112 ARHGAP39 SLC39A4 GPAA1 MIR939 ADCK5 EXOSC4 LOC101928953 C8orf82 SHARPIN

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

ribosomal protein

Gene Ontology Categories:

Process(es)

cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
rRNA processing
cell proliferation
ribosome biogenesis
regulation of cell cycle

Function(s)

protein binding
ribonucleoprotein complex binding
poly(A) RNA binding