Hs04032751_cn

• Gene Symbol: GRIN3B
• Assay Reference Genome Location: Chr.19:1001510 on build GRCh38
• Cytoband: 19p13.3

Target Gene Details

• Entrez Gene ID: 116444
• Gene Name: glutamate ionotropic receptor NMDA type subunit 3B
• Gene Aliases: GluN3B, NR3B
• Location: Chr.19:1000419-1009814 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GRIN3B	NM_138690.2			NP_619635.1
	AY507106.1			AAS87020.1
	AY507107.1			AAS87021.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv9662	Chr.19:893394 - 1317740 on Build GRCh38	Gain	GRIN3B ABCA7 POLR2E CBARP C19orf24 RNU6-9 GPX4 CNN2 ATP5D MIDN SBNO2 R3HDM4 KISS1R ARHGAP45 WDR18 STK11 LOC102725180 TMEM259 CIRBP EFNA2 CIRBP-AS1 ARID3A RNU6-2 LOC105372235
nsv1160555	Chr.19:887275 - 1346084 on Build GRCh38	Deletion	ABCA7 CBARP RNU6-9 CNN2 MIDN SBNO2 R3HDM4 ARHGAP45 WDR18 LOC102725180 CIRBP EFNA2 CIRBP-AS1 LOC105372235 GRIN3B POLR2E C19orf24 MED16 GPX4 ATP5D KISS1R STK11 TMEM259 ARID3A RNU6-2
nsv578188	Chr.19:923744 - 1059005 on Build GRCh38	Loss	GRIN3B ABCA7 WDR18 TMEM259 ARID3A RNU6-2 CNN2 LOC105372235
nsv469845	Chr.19:951640 - 1144486 on Build GRCh38	Loss	GRIN3B SBNO2 ABCA7 POLR2E ARHGAP45 WDR18 TMEM259 ARID3A RNU6-2 GPX4 CNN2 LOC105372235
esv2758743	Chr.19:951641 - 1544934 on Build GRCh38	Gain+Loss	ABCA7 CBARP C19orf25 DAZAP1 CNN2 MIDN SBNO2 APC2 ARHGAP45 WDR18 LOC102725180 CIRBP EFNA2 CIRBP-AS1 LOC105372235 GRIN3B POLR2E RPS15 C19orf24 GAMT GPX4 ATP5D PLK5 MUM1 REEP6 ADAMTSL5 STK11 TMEM259 PCSK4 ARID3A RNU6-2 NDUFS7
nsv953938	Chr.19:355801 - 1104501 on Build GRCh38	Deletion	MIR3187 ABCA7 PTBP1 MISP RNF126 MIR4745 RNU6-9 ODF3L2 CNN2 THEG BSG R3HDM4 ARHGAP45 WDR18 FSTL3 TPGS1 POLRMT PRTN3 LOC105372235 C2CD4C GRIN3B POLR2E PRSS57 MADCAM1 MED16 FGF22 GPX4 CFD GZMM KISS1R TMEM259 CDC34 AZU1 SHC2 ELANE HCN2 PALM LOC101928450 ARID3A PLPPR3 RNU6-2
nsv470101	Chr.19:401714 - 1008505 on Build GRCh38	Loss	MIR3187 PTBP1 MISP RNF126 MIR4745 RNU6-9 ODF3L2 BSG R3HDM4 WDR18 FSTL3 TPGS1 POLRMT PRTN3 LOC105372235 C2CD4C GRIN3B PRSS57 MADCAM1 MED16 FGF22 CFD GZMM KISS1R CDC34 AZU1 SHC2 ELANE HCN2 PALM LOC101928450 ARID3A PLPPR3

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

ionotropic glutamate receptor signaling pathway
protein insertion into membrane
regulation of calcium ion transport
calcium ion transmembrane transport

Function(s)

NMDA glutamate receptor activity
extracellular-glutamate-gated ion channel activity
cation channel activity
calcium channel activity
glycine binding
neurotransmitter receptor activity
neurotransmitter binding