Hs04027977_cn

• Gene Symbol: GRIN3B
• Assay Reference Genome Location: Chr.19:1006819 on build GRCh38
• Cytoband: 19p13.3

Target Gene Details

• Entrez Gene ID: 116444
• Gene Name: glutamate ionotropic receptor NMDA type subunit 3B
• Gene Aliases: GluN3B, NR3B
• Location: Chr.19:1000419-1009814 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GRIN3B	NM_138690.2			NP_619635.1
	XM_017026243.1			XP_016881732.1
	AY507106.1			AAS87020.1
	AY507107.1			AAS87021.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv9662	Chr.19:893394 - 1317740 on Build GRCh38	Gain	C19orf24 TMEM259 ABCA7 CNN2 POLR2E ATP5D ARHGAP45 CIRBP ARID3A EFNA2 LOC102725180 R3HDM4 KISS1R LOC105372235 RNU6-2 SBNO2 CIRBP-AS1 GRIN3B RNU6-9 WDR18 CBARP STK11 GPX4 MIDN
nsv1160555	Chr.19:887275 - 1346084 on Build GRCh38	Deletion	CNN2 ARHGAP45 CIRBP LOC102725180 R3HDM4 KISS1R RNU6-2 SBNO2 GRIN3B STK11 GPX4 MIDN MED16 C19orf24 TMEM259 ABCA7 POLR2E ATP5D ARID3A EFNA2 LOC105372235 CIRBP-AS1 RNU6-9 WDR18 CBARP
nsv578188	Chr.19:923744 - 1059005 on Build GRCh38	Loss	LOC105372235 TMEM259 ABCA7 CNN2 RNU6-2 GRIN3B WDR18 ARID3A
nsv469845	Chr.19:951640 - 1144486 on Build GRCh38	Loss	LOC105372235 TMEM259 ABCA7 CNN2 RNU6-2 SBNO2 GRIN3B POLR2E WDR18 ARHGAP45 GPX4 ARID3A
esv2758743	Chr.19:951641 - 1544934 on Build GRCh38	Gain+Loss	PCSK4 CNN2 REEP6 NDUFS7 ARHGAP45 CIRBP LOC102725180 RPS15 PLK5 RNU6-2 SBNO2 GRIN3B STK11 GPX4 C19orf25 MIDN C19orf24 TMEM259 ABCA7 MUM1 POLR2E ATP5D APC2 ARID3A EFNA2 LOC105372235 CIRBP-AS1 WDR18 DAZAP1 CBARP ADAMTSL5 GAMT
nsv953938	Chr.19:355801 - 1104501 on Build GRCh38	Deletion	CNN2 GZMM FGF22 MIR4745 ARHGAP45 RNF126 R3HDM4 KISS1R RNU6-2 GRIN3B POLRMT ODF3L2 GPX4 MED16 PALM C2CD4C TMEM259 ABCA7 BSG POLR2E AZU1 CDC34 PTBP1 ARID3A MIR3187 PLPPR3 LOC105372235 FSTL3 ELANE PRSS57 RNU6-9 MISP HCN2 LOC101928450 WDR18 PRTN3 TPGS1 THEG SHC2 MADCAM1 CFD
nsv470101	Chr.19:401714 - 1008505 on Build GRCh38	Loss	GZMM FGF22 MIR4745 RNF126 R3HDM4 KISS1R GRIN3B POLRMT ODF3L2 MED16 PALM C2CD4C BSG AZU1 CDC34 PTBP1 ARID3A MIR3187 PLPPR3 LOC105372235 FSTL3 ELANE PRSS57 RNU6-9 MISP HCN2 LOC101928450 WDR18 PRTN3 TPGS1 SHC2 MADCAM1 CFD

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

ionotropic glutamate receptor signaling pathway
protein insertion into membrane
regulation of calcium ion transport
calcium ion transmembrane transport

Function(s)

NMDA glutamate receptor activity
extracellular-glutamate-gated ion channel activity
cation channel activity
calcium channel activity
glycine binding
neurotransmitter receptor activity
neurotransmitter binding