Hs03962430_cn

• Gene Symbol: CD300A
• Assay Reference Genome Location: Chr.17:74483109 on build GRCh38
• Cytoband: 17q25.1

Target Gene Details

• Entrez Gene ID: 11314
• Gene Name: CD300a molecule
• Gene Aliases: CLM-8, CMRF-35-H9, CMRF-35H, CMRF35-H, CMRF35-H9, CMRF35H, CMRF35H9, IGSF12, IRC1, IRC1/IRC2, IRC2, IRp60
• Location: Chr.17:74466320-74484798 on Build GRCh38
• Assay Gene Location: Within Intron 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CD300A	NM_001256841.1			NP_001243770.1
	NM_007261.3			NP_009192.2
	XM_005256990.2			XP_005257047.1
	XM_005256991.4			XP_005257048.1
	XM_005256992.4			XP_005257049.1
	XM_006721656.3			XP_006721719.1
	XM_011524254.2			XP_011522556.1
	AF020314.1			AAD01646.1
	AF161346.1			AAF28906.1
	AJ010101.1			CAB52291.1
	AJ010102.1			CAB52292.1
	AJ010103.1			CAB52293.1
	AJ224864.1			CAB55347.1
	AJ238323.1			CAB66145.1
	AK309631.1
	AK309636.1
	BC032352.1			AAH32352.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv12e196	Chr.17:73675043 - 74565539 on Build GRCh38	Duplication	CD300LB BTBD17 KIF19 TTYH2 GPRC5C MGC16275 GPR142 LOC100130520 LINC00469 CD300A CD300C RPL38 LOC100134391 LOC400620 DNAI2
nsv470600	Chr.17:74466882 - 74550979 on Build GRCh38	Loss	CD300A CD300LB CD300C
esv2761978	Chr.17:73835799 - 74684915 on Build GRCh38	Gain	CD300LB BTBD17 LOC101928343 C17orf77 KIF19 CD300LD TTYH2 GPRC5C MGC16275 GPR142 LOC100130520 CD300A CD300E CD300C RPL38 DNAI2 RAB37
esv3641230	Chr.17:73831787 - 74694861 on Build GRCh38	Gain	CD300LB BTBD17 CD300LF LOC101928343 C17orf77 KIF19 CD300LD TTYH2 GPRC5C MGC16275 GPR142 LOC100130520 CD300A CD300E CD300C RPL38 DNAI2 RAB37
dgv3282n100	Chr.17:73814343 - 74719597 on Build GRCh38	Gain	CD300LB BTBD17 CD300LF LOC101928343 C17orf77 KIF19 CD300LD TTYH2 GPRC5C MGC16275 GPR142 LOC100130520 LINC00469 CD300A CD300E CD300C RPL38 DNAI2 RAB37
esv33995	Chr.17:74261053 - 74732093 on Build GRCh38	Loss	CD300LB BTBD17 CD300LF LOC101928343 C17orf77 KIF19 CD300LD TTYH2 GPRC5C GPR142 LOC100130520 CD300A CD300E CD300C DNAI2 RAB37
nsv517569	Chr.17:73837862 - 74685802 on Build GRCh38	Gain+Loss	CD300LB BTBD17 LOC101928343 C17orf77 KIF19 CD300LD TTYH2 GPRC5C MGC16275 GPR142 LOC100130520 CD300A CD300E CD300C RPL38 DNAI2 RAB37
dgv5768n54	Chr.17:73826016 - 74706775 on Build GRCh38	Gain	CD300LB BTBD17 CD300LF LOC101928343 C17orf77 KIF19 CD300LD TTYH2 GPRC5C MGC16275 GPR142 LOC100130520 LINC00469 CD300A CD300E CD300C RPL38 DNAI2 RAB37
esv3573820	Chr.17:73817932 - 74694378 on Build GRCh38	Gain	CD300LB BTBD17 CD300LF LOC101928343 C17orf77 KIF19 CD300LD TTYH2 GPRC5C MGC16275 GPR142 LOC100130520 LINC00469 CD300A CD300E CD300C RPL38 DNAI2 RAB37
dgv5774n54	Chr.17:74428381 - 74673021 on Build GRCh38	Gain	LOC100130520 CD300A CD300LB CD300E CD300C LOC101928343 C17orf77 CD300LD GPRC5C RAB37

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

immunoglobulin receptor superfamily

Gene Ontology Categories:

Process(es)

immune system process
cell adhesion
signal transduction
negative regulation of B cell proliferation
positive regulation of phosphoprotein phosphatase activity
negative regulation of mast cell activation involved in immune response
negative regulation of mast cell degranulation
negative regulation of MAP kinase activity
negative regulation of fibroblast proliferation
regulation of immune response
regulation of T cell receptor signaling pathway
negative regulation of B cell receptor signaling pathway
negative regulation of NK T cell activation
negative regulation of phagocytosis, engulfment
negative regulation of neutrophil activation
negative regulation of eosinophil activation
negative regulation of activation of JAK2 kinase activity
negative regulation of eosinophil migration

Function(s)

phosphatidylserine binding
protein binding
phosphatidylethanolamine binding
signaling receptor activity