Hs03753891_cn

• Gene Symbol: BNIP3
• Assay Reference Genome Location: Chr.10:131976873 on build GRCh38
• Cytoband: 10q26.3

Target Gene Details

• Entrez Gene ID: 664
• Gene Name: BCL2 interacting protein 3
• Gene Aliases: NIP3
• Location: Chr.10:131967683-131982013 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
BNIP3	NM_004052.3			NP_004043.3
	AF002697.1			AAC16738.1
	AK222626.1			BAD96346.1
	AK295136.1
	BC021989.1			AAH21989.1
	BC067818.1			AAH67818.1
	BC080643.1			AAH80643.1
	HY049371.1
	U15174.1			AAC00022.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3624956	Chr.10:131249138 - 132223150 on Build GRCh38	Gain	JAKMIP3 DPYSL4 PPP2R2D LINC01164 STK32C TCERG1L BNIP3
nsv1054934	Chr.10:130334322 - 133158679 on Build GRCh38	Gain	LINC01166 JAKMIP3 PWWP2B CFAP46 LOC105378568 C10orf91 MIR378C LRRC27 LINC01168 INPP5A TCERG1L ADGRA1-AS1 DPYSL4 PPP2R2D TCERG1L-AS1 LOC107984282 LINC01167 LINC01164 ADGRA1 STK32C NKX6-2 BNIP3
nsv825651	Chr.10:131975920 - 131986071 on Build GRCh38	Gain	BNIP3
nsv825650	Chr.10:131914064 - 132056715 on Build GRCh38	Gain	JAKMIP3 PPP2R2D BNIP3

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

mitophagy
response to hypoxia
apoptotic process
cell death
granzyme-mediated apoptotic signaling pathway
positive regulation of autophagy
negative regulation of mitochondrial fusion
positive regulation of cardiac muscle cell apoptotic process
positive regulation of macroautophagy
mitochondrial protein catabolic process
positive regulation of apoptotic process
negative regulation of apoptotic process
positive regulation of programmed cell death
positive regulation of protein complex disassembly
mitochondrial fragmentation involved in apoptotic process
negative regulation of membrane potential
regulation of mitochondrial membrane permeability
autophagic cell death
brown fat cell differentiation
neuron apoptotic process
defense response to virus
response to hyperoxia
negative regulation of cell death
cellular response to hydrogen peroxide
cellular response to mechanical stimulus
cellular response to cobalt ion
cellular response to hypoxia
reactive oxygen species metabolic process
positive regulation of mitochondrial fission
positive regulation of release of cytochrome c from mitochondria
mitochondrial outer membrane permeabilization
toxin transport
regulation of aerobic respiration
intrinsic apoptotic signaling pathway in response to hypoxia
negative regulation of reactive oxygen species metabolic process

Function(s)

protein binding
identical protein binding
protein homodimerization activity
protein heterodimerization activity
GTPase binding