Hs03688129_cn

• Gene Symbol: BOP1
• Assay Reference Genome Location: Chr.8:144282807 on build GRCh38
• Cytoband: 8q24.3

Target Gene Details

• Entrez Gene ID: 23246
• Gene Name: block of proliferation 1
• Gene Aliases: -
• Location: Chr.8:144262046-144291438 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
BOP1	NM_015201.4			NP_056016.1
	AB060694.1			BAB70666.1
	AK024840.1
	AK290677.1
	AK293719.1
	AK315612.1
	BC001086.2			AAH01086.2
	BC005160.2			AAH05160.2
	BC007274.1			AAH07274.1
	BC013787.1			AAH13787.1
	BC013980.2			AAH13980.1
	BC017674.2			AAH17674.1
	BQ711345.1
	D50914.1			BAA09473.1
	DA510177.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv12434n54	Chr.8:144270080 - 144516801 on Build GRCh38	Loss	FOXH1 PPP1R16A DGAT1 RECQL4 MIR6849 SLC39A4 MIR1234 HSF1 TONSL-AS1 TMEM249 MIR6848 LOC101928902 CYHR1 MIR939 FBXL6 BOP1 SCRT1 VPS28 MIR6893 CPSF1 TONSL GPT MFSD3 LOC101928953 KIFC2 SLC52A2 ADCK5
nsv470249	Chr.8:143889098 - 144519234 on Build GRCh38	Loss	FOXH1 PARP10 EXOSC4 PPP1R16A DGAT1 LRRC14 SMPD5 RECQL4 MIR6849 SLC39A4 MIR1234 HSF1 MIR6846 TONSL-AS1 TMEM249 MIR6847 MIR6848 SPATC1 LOC101928902 CYHR1 MAF1 CYC1 MIR939 SHARPIN FBXL6 BOP1 GRINA SCRT1 VPS28 MIR6893 OPLAH CPSF1 MIR661 SCX MIR7112 TONSL GPT MFSD3 HGH1 LOC101928953 PLEC WDR97 GPAA1 MROH1 KIFC2 SLC52A2 ADCK5
nsv515809	Chr.8:143904439 - 144519234 on Build GRCh38	Gain+Loss	FOXH1 PARP10 EXOSC4 PPP1R16A DGAT1 LRRC14 SMPD5 RECQL4 MIR6849 SLC39A4 MIR1234 HSF1 MIR6846 TONSL-AS1 TMEM249 MIR6847 MIR6848 SPATC1 LOC101928902 CYHR1 MAF1 CYC1 MIR939 SHARPIN FBXL6 BOP1 GRINA SCRT1 VPS28 MIR6893 OPLAH CPSF1 MIR661 SCX MIR7112 TONSL GPT MFSD3 HGH1 LOC101928953 PLEC WDR97 GPAA1 MROH1 KIFC2 SLC52A2 ADCK5
nsv1025071	Chr.8:144044224 - 144300847 on Build GRCh38	Gain	MAF1 CYC1 SHARPIN EXOSC4 BOP1 SMPD5 OPLAH SCX HSF1 MIR6846 MIR7112 HGH1 WDR97 GPAA1 MIR6847 MROH1 SPATC1
nsv428208	Chr.8:144041826 - 144722291 on Build GRCh38	Gain	FOXH1 EXOSC4 LRRC24 PPP1R16A DGAT1 LRRC14 SMPD5 C8orf82 RECQL4 MIR6849 SLC39A4 MIR1234 HSF1 MIR6846 TONSL-AS1 TMEM249 ZNF251 MIR6847 MIR6848 SPATC1 LOC101928902 CYHR1 MAF1 CYC1 MIR939 SHARPIN FBXL6 BOP1 SCRT1 VPS28 MIR6893 OPLAH CPSF1 SCX MIR7112 TONSL GPT MFSD3 HGH1 LOC101928953 ARHGAP39 WDR97 GPAA1 MROH1 KIFC2 SLC52A2 ADCK5

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

ribosomal protein

Gene Ontology Categories:

Process(es)

cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
rRNA processing
cell proliferation
ribosome biogenesis
regulation of cell cycle

Function(s)

protein binding
ribonucleoprotein complex binding
poly(A) RNA binding