Hs03467554_cn

• Gene Symbol: SEMA3F
• Assay Reference Genome Location: Chr.3:50166306 on build GRCh38
• Cytoband: 3p21.31

Target Gene Details

• Entrez Gene ID: 6405
• Gene Name: semaphorin 3F
• Gene Aliases: SEMA-IV, SEMA4, SEMAK
• Location: Chr.3:50155045-50189075 on Build GRCh38
• Assay Gene Location: Within Intron 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SEMA3F	NM_001318798.1			NP_001305727.1
	NM_001318800.1			NP_001305729.1
	NM_004186.4			NP_004177.3
	XM_005265381.4			XP_005265438.1
	XM_005265382.4			XP_005265439.1
	XM_006713290.3			XP_006713353.1
	XM_011533998.2			XP_011532300.1
	XM_011534000.2			XP_011532302.1
	AB209259.1			BAD92496.1
	BC042914.1			AAH42914.1
	BF058597.1
	BQ949723.1
	U33920.1			AAC50568.1
	U38276.1			AAB18276.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2759148	Chr.3:50161045 - 50333946 on Build GRCh38	Loss	MIR566 LSMEM2 RASSF1 NAT6 TUSC2 MIR5787 SEMA3F SEMA3B GNAT1 HYAL1 SEMA3B-AS1 SLC38A3 MIR6872 HYAL3 IFRD2 HYAL2 GNAI2
nsv523560	Chr.3:50134964 - 50314769 on Build GRCh38	Loss	MIR566 LSMEM2 NAT6 MIR5787 SEMA3F SEMA3B GNAT1 HYAL1 LOC107986035 SEMA3B-AS1 SEMA3F-AS1 SLC38A3 MIR6872 HYAL3 IFRD2 GNAI2
dgv602n27	Chr.3:50140578 - 50287241 on Build GRCh38	Loss	SEMA3B-AS1 MIR566 LSMEM2 SEMA3F-AS1 SLC38A3 MIR6872 MIR5787 SEMA3F SEMA3B GNAT1 GNAI2 LOC107986035
nsv834692	Chr.3:50161052 - 50356033 on Build GRCh38	Loss	MIR566 LSMEM2 ZMYND10 RASSF1 NAT6 TUSC2 MIR5787 SEMA3F RASSF1-AS1 SEMA3B GNAT1 HYAL1 SEMA3B-AS1 TMEM115 CYB561D2 NPRL2 SLC38A3 MIR6872 HYAL3 IFRD2 HYAL2 GNAI2
dgv8316n54	Chr.3:50115923 - 50299991 on Build GRCh38	Loss	MIR566 LSMEM2 NAT6 MIR5787 RBM5 SEMA3F SEMA3B GNAT1 HYAL1 LOC107986035 SEMA3B-AS1 SEMA3F-AS1 SLC38A3 MIR6872 HYAL3 IFRD2 GNAI2
nsv515986	Chr.3:50066874 - 50254353 on Build GRCh38	Loss	MIR566 SEMA3F-AS1 SLC38A3 RBM5-AS1 MIR5787 RBM5 SEMA3F RBM6 GNAT1 GNAI2 LOC107986035
nsv470561	Chr.3:50121341 - 50547568 on Build GRCh38	Loss	MIR566 NAT6 MIR5787 SEMA3F RASSF1-AS1 SEMA3B TMEM115 CYB561D2 NPRL2 HYAL3 IFRD2 GNAI2 LSMEM2 ZMYND10 RASSF1 TUSC2 GNAT1 HYAL1 CACNA2D2 LOC107986035 SEMA3B-AS1 SEMA3F-AS1 SLC38A3 MIR6872 HYAL2
nsv523662	Chr.3:50107518 - 50547568 on Build GRCh38	Loss	MIR566 NAT6 MIR5787 RBM5 SEMA3F RASSF1-AS1 SEMA3B TMEM115 CYB561D2 NPRL2 HYAL3 IFRD2 GNAI2 LSMEM2 ZMYND10 RASSF1 TUSC2 GNAT1 HYAL1 CACNA2D2 LOC107986035 SEMA3B-AS1 SEMA3F-AS1 SLC38A3 MIR6872 HYAL2
nsv834690	Chr.3:50064402 - 50263192 on Build GRCh38	Loss	MIR566 SEMA3F-AS1 SLC38A3 RBM5-AS1 MIR5787 RBM5 SEMA3F RBM6 GNAT1 GNAI2 LOC107986035
nsv954855	Chr.3:50152468 - 50439169 on Build GRCh38	Deletion	MIR566 NAT6 MIR5787 SEMA3F RASSF1-AS1 SEMA3B TMEM115 CYB561D2 NPRL2 HYAL3 IFRD2 GNAI2 LSMEM2 ZMYND10 RASSF1 TUSC2 GNAT1 HYAL1 CACNA2D2 LOC107986035 SEMA3B-AS1 SEMA3F-AS1 SLC38A3 MIR6872 HYAL2

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

membrane-bound signaling molecule, intercellular signal molecule

Gene Ontology Categories:

Process(es)

neural crest cell migration
axon guidance
facial nerve structural organization
trigeminal nerve structural organization
nerve development
branchiomotor neuron axon guidance
positive regulation of cell migration
ventral trunk neural crest cell migration
negative regulation of axon extension involved in axon guidance
axon extension involved in axon guidance
negative chemotaxis
sympathetic ganglion development
semaphorin-plexin signaling pathway
sympathetic neuron projection extension
sympathetic neuron projection guidance
neural crest cell migration involved in autonomic nervous system development
semaphorin-plexin signaling pathway involved in neuron projection guidance
semaphorin-plexin signaling pathway involved in axon guidance

Function(s)

semaphorin receptor binding
neuropilin binding
chemorepellent activity