Hs03020252_cn

• Gene Symbol: LOXL1
• Assay Reference Genome Location: Chr.15:73947072 on build GRCh38
• Cytoband: 15q24.1

Target Gene Details

• Entrez Gene ID: 4016
• Gene Name: lysyl oxidase like 1
• Gene Aliases: LOL, LOXL
• Location: Chr.15:73926451-73952141 on Build GRCh38
• Assay Gene Location: Overlaps Intron 5 - Exon 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LOXL1	NM_005576.3			NP_005567.2
	XM_017022179.1			XP_016877668.1
	AK303982.1
	AK314222.1
	BC015090.2			AAH15090.1
	BC068542.1			AAH68542.1
	L21186.1			AAA50162.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3581762	Chr.15:73944743 - 73947178 on Build GRCh38	Loss	LOXL1
esv2760040	Chr.15:73922773 - 74172575 on Build GRCh38	Gain+Loss	LOC732265 STOML1 LOXL1-AS1 GOLGA6A LOC283731 ISLR2 PML LOXL1
nsv1121512	Chr.15:72670085 - 75273877 on Build GRCh38	Deletion	LOC732265 PPCDC UBL7-AS1 SCAMP5 GOLGA6A COX5A PML ADPGK LOC105376731 CPLX3 RPP25 ULK3 CYP1A1 NPTN-IT1 C15orf39 C15orf59-AS1 REC114 EDC3 ISLR2 MIR6882 CD276 ISLR HIGD2B LOC101929333 ARID3B SCAMP2 LOC102723750 TBC1D21 LOC107984728 GOLGA6C ADPGK-AS1 STRA6 LOXL1 CSK MIR6881 NEO1 LOXL1-AS1 BBS4 MIR4513 SEMA7A CYP11A1 STOML1 MPI CYP1A2 NPTN CLK3 FAM219B C15orf59 LOC729739 UBL7 LMAN1L LOC283731 HCN4 CCDC33

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

oxidase

Gene Ontology Categories:

Process(es)

protein deamination
extracellular matrix organization
response to lipopolysaccharide
aorta development
oxidation-reduction process

Function(s)

copper ion binding
oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor