Hs02989737_cn

• Gene Symbol: HSF4
• Assay Reference Genome Location: Chr.16:67164454 on build GRCh38
• Cytoband: 16q22.1

Target Gene Details

• Entrez Gene ID: 3299
• Gene Name: heat shock transcription factor 4
• Gene Aliases: CTM, CTRCT5
• Location: Chr.16:67163385-67169945 on Build GRCh38
• Assay Gene Location: Overlaps Intron 2 - Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
HSF4	NM_001040667.2			NP_001035757.1
	NM_001538.3			NP_001529.2
	AK307211.1
	AK308638.1
	BM805441.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv522852	Chr.16:67153308 - 68071571 on Build GRCh38	Gain	LRRC36 CTRL PLEKHG4 LOC100505942 RANBP10 LRRC29 LOC107984813 DPEP2 HSF4 THAP11 CENPT FBXL8 TRADD EXOC3L1 ELMO3 GFOD2 DPEP3 CARMIL2 SLC9A5 DDX28 E2F4 ZDHHC1 MIR328 ENKD1 C16orf86 LOC105369155 TPPP3 SLC12A4 DUS2 NUTF2 AGRP FAM65A PSMB10 NRN1L TSNAXIP1 KCTD19 EDC4 KIAA0895L ACD FHOD1 HSD11B2 TMEM208 LOC100131303 PSKH1 LCAT PARD6A CTCF ATP6V0D1 NOL3
nsv827707	Chr.16:67148355 - 67289296 on Build GRCh38	Loss	ELMO3 TMEM208 PLEKHG4 LRRC29 SLC9A5 HSF4 E2F4 B3GNT9 MIR328 KIAA0895L FBXL8 NOL3 TRADD EXOC3L1 LOC105369155 FHOD1 C16orf70
nsv952044	Chr.16:67141198 - 67244397 on Build GRCh38	Deletion	ELMO3 TMEM208 LRRC29 HSF4 E2F4 B3GNT9 MIR328 KIAA0895L FBXL8 NOL3 TRADD EXOC3L1 LOC105369155 FHOD1 C16orf70
nsv1160429	Chr.16:67161549 - 67220197 on Build GRCh38	Deletion	HSF4 E2F4 ELMO3 MIR328 KIAA0895L FBXL8 NOL3 EXOC3L1 LOC105369155 LRRC29
nsv524363	Chr.16:67136529 - 68071571 on Build GRCh38	Loss	LRRC36 CTRL PLEKHG4 LOC100505942 RANBP10 LRRC29 LOC107984813 DPEP2 HSF4 THAP11 CENPT FBXL8 TRADD EXOC3L1 ELMO3 GFOD2 DPEP3 CARMIL2 SLC9A5 DDX28 E2F4 B3GNT9 ZDHHC1 MIR328 ENKD1 C16orf86 LOC105369155 C16orf70 TPPP3 SLC12A4 DUS2 NUTF2 AGRP FAM65A PSMB10 NRN1L TSNAXIP1 KCTD19 EDC4 KIAA0895L ACD FHOD1 HSD11B2 TMEM208 LOC100131303 PSKH1 LCAT PARD6A CTCF ATP6V0D1 NOL3

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

winged helix/forkhead transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
visual perception
positive regulation of cell proliferation
histone H3-K9 demethylation
camera-type eye development
positive regulation of cell differentiation
positive regulation of transcription from RNA polymerase II promoter
cell development
protein homotrimerization

Function(s)

transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
sequence-specific DNA binding