Hs02984797_cn

• Gene Symbol: SEMA4C
• Assay Reference Genome Location: Chr.2:96860506 on build GRCh38
• Cytoband: 2q11.2

Target Gene Details

• Entrez Gene ID: 54910
• Gene Name: semaphorin 4C
• Gene Aliases: M-SEMA-F, SEMACL1, SEMAF, SEMAI
• Location: Chr.2:96859736-96870943 on Build GRCh38
• Assay Gene Location: Within Exon 18

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SEMA4C	NM_017789.4	15	2782	NP_060259.4
	XM_011511378.2	15	2890	XP_011509680.1
	XM_011511379.2	15	2887	XP_011509681.1
	XM_011511380.1	15	3225	XP_011509682.1
	XM_011511381.1	15	2859	XP_011509683.1
	XM_011511382.2	15	2818	XP_011509684.1
	XM_011511383.1	15	2830	XP_011509685.1
	XM_017004393.1	14	3312	XP_016859882.1
	XM_017004394.1	13	2434	XP_016859883.1
	AB051526.1	13	3012	BAB21830.1
	AF258577.1	5	1339	AAG23780.1
	AF370374.1	2	1856	AAQ15210.1
	AK000376.1	7	1722	BAA91124.1
	AK075388.1	3	1430	BAC11588.1
	AK126512.1	3	2611
	AY358842.1	15	2755	AAQ89201.1
	BC017476.1	9	2058	AAH17476.2
	BC062984.1	7	1754	AAH62984.1
	BC109103.1			AAI09104.1
	BC109104.1			AAI09105.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv526313	Chr.2:96667755 - 96994882 on Build GRCh38	Loss	FAM178B LOC101927053 FER1L5 SEMA4C CNNM3 LMAN2L ANKRD39 MIR3127 ANKRD23 CNNM4
dgv607e201	Chr.2:95855884 - 97561622 on Build GRCh38	Deletion	STARD7 CIAO1 LOC107984110 FAHD2CP FAHD2B FER1L5 NCAPH ANKRD36B LMAN2L ANKRD36 SNRNP200 DUSP2 ITPRIPL1 TMEM127 CNNM3 MIR3127 NEURL3 STARD7-AS1 LOC105373495 LOC100506123 LOC100506076 ASTL LOC105373496 ANKRD23 KANSL3 LOC653924 FAM178B LOC101927053 SEMA4C GPAT2 ANKRD36C ANKRD39 ARID5A ADRA2B CNNM4
nsv1135873	Chr.2:95981454 - 97579645 on Build GRCh38	Deletion	STARD7 CIAO1 LOC107984110 FAHD2CP FAHD2B FER1L5 NCAPH ANKRD36B LMAN2L ANKRD36 SNRNP200 DUSP2 ITPRIPL1 TMEM127 CNNM3 MIR3127 NEURL3 STARD7-AS1 LOC105373495 LOC100506123 LOC100506076 ASTL LOC105373496 ANKRD23 KANSL3 LOC653924 FAM178B LOC101927053 SEMA4C GPAT2 ANKRD36C ANKRD39 ARID5A ADRA2B CNNM4
esv3425717	Chr.2:95859900 - 97515905 on Build GRCh38	Duplication	STARD7 CIAO1 LOC107984110 FAHD2CP FAHD2B FER1L5 NCAPH ANKRD36B LMAN2L ANKRD36 SNRNP200 DUSP2 ITPRIPL1 TMEM127 CNNM3 MIR3127 NEURL3 STARD7-AS1 LOC105373495 LOC100506123 LOC100506076 ASTL LOC105373496 ANKRD23 KANSL3 LOC653924 FAM178B LOC101927053 SEMA4C GPAT2 ANKRD36C ANKRD39 ARID5A ADRA2B CNNM4

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

membrane-bound signaling molecule, intercellular signal molecule

Gene Ontology Categories:

Process(es)

neural crest cell migration
neural tube closure
cell migration in hindbrain
cerebellum development
positive regulation of cell migration
positive regulation of stress-activated MAPK cascade
muscle cell differentiation
negative regulation of axon extension involved in axon guidance
negative chemotaxis
semaphorin-plexin signaling pathway

Function(s)

protein binding
semaphorin receptor binding
neuropilin binding
chemorepellent activity