Hs02640854_cn

• Gene Symbol: SEC61A1
• Assay Reference Genome Location: Chr.3:128052590 on build GRCh38
• Cytoband: 3q21.3

Target Gene Details

• Entrez Gene ID: 29927
• Gene Name: Sec61 translocon alpha 1 subunit
• Gene Aliases: HSEC61, SEC61, SEC61A
• Location: Chr.3:128052369-128071683 on Build GRCh38
• Assay Gene Location: Overlaps Exon 1 - Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SEC61A1	NM_013336.3			NP_037468.1
	AF077032.1			AAD27765.1
	AF084458.1			AAD39847.1
	AF346602.1			AAK29083.1
	AK027423.1
	AK074706.1
	AK299118.1
	AL832821.1			CAI46127.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1001879	Chr.3:127956099 - 128143493 on Build GRCh38	Gain	RUVBL1-AS1 KBTBD12 RUVBL1 SEC61A1
nsv3991	Chr.3:128048752 - 128081671 on Build GRCh38	Insertion	RUVBL1-AS1 RUVBL1 SEC61A1
nsv1002685	Chr.3:127819453 - 128455596 on Build GRCh38	Gain	RUVBL1-AS1 KBTBD12 MGLL RUVBL1 EEFSEC SEC61A1

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transporter

Gene Ontology Categories:

Process(es)

SRP-dependent cotranslational protein targeting to membrane
posttranslational protein targeting to membrane
endoplasmic reticulum organization
cell growth
response to interferon-gamma
IRE1-mediated unfolded protein response
protein targeting to ER

Function(s)

protein binding
ribosome binding