Hs02634348_cn

• Gene Symbol: KLRG1
• Assay Reference Genome Location: Chr.12:9160306 on build GRCh38
• Cytoband: 12p13.31

Target Gene Details

• Entrez Gene ID: 10219
• Gene Name: killer cell lectin like receptor G1
• Gene Aliases: 2F1, CLEC15A, MAFA, MAFA-2F1, MAFA-L, MAFA-LIKE
• Location: Chr.12:8989079-9255692 on Build GRCh38
• Assay Gene Location: Within Intron 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
KLRG1	XM_017018685.1			XP_016874174.1

Target Gene Details

• Entrez Gene ID: 5858
• Gene Name: PZP, alpha-2-macroglobulin like
• Gene Aliases: CPAMD6
• Location: Chr.12:9140730-9208370 on Build GRCh38
• Assay Gene Location: Overlaps Intron 24 - Exon 24

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PZP	NM_002864.2			NP_002855.2
	XM_011520804.2			XP_011519106.1
	XM_011520805.2			XP_011519107.1
	XM_011520806.1			XP_011519108.1
	XM_017019763.1			XP_016875252.1
	XM_017019764.1			XP_016875253.1
	XM_017019765.1			XP_016875254.1
	XM_017019766.1			XP_016875255.1
	AK313639.1
	BC111756.1			AAI11757.1
	X54380.1			CAA38255.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv523958	Chr.12:9150844 - 9396476 on Build GRCh38	Loss	LOC105369649 MIR1244-3 LINC00987 A2MP1 LOC101930452 LOC101928030 LOC642846 KLRG1 PZP
nsv1051530	Chr.12:8442286 - 9951690 on Build GRCh38	Gain	LOC105369649 MIR1244-3 CLEC2B KLRB1 CLECL1 CLEC12A LOC374443 LOC100506159 LOC105369728 KLRG1 KLRF2 M6PR AICDA LINC00987 A2MP1 LOC101930452 MFAP5 LOC105376678 CLEC4E CLEC6A LOC400002 A2ML1 DDX12P CLEC2D LOC642846 CLEC4D RIMKLB LINC00612 A2M-AS1 CLEC2A CD69 A2M LOC728715 PHC1 LOC101928030 OVOS KLRF1 PZP
nsv527404	Chr.12:9098005 - 9282648 on Build GRCh38	Gain	MIR1244-3 A2M LINC00987 A2MP1 KLRG1 PZP
nsv557355	Chr.12:9157399 - 9376419 on Build GRCh38	Gain	LOC105369649 MIR1244-3 LINC00987 A2MP1 LOC101930452 LOC101928030 LOC642846 KLRG1 PZP

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor, protease inhibitor

Gene Ontology Categories:

Process(es)

inflammatory response
cellular defense response
cell surface receptor signaling pathway
innate immune response
female pregnancy
negative regulation of endopeptidase activity

Function(s)

receptor activity
protein binding
carbohydrate binding
endopeptidase inhibitor activity
serine-type endopeptidase inhibitor activity