Hs02624582_cn

• Gene Symbol: SMC3
• Assay Reference Genome Location: Chr.10:110583444 on build GRCh38
• Cytoband: 10q25.2

Target Gene Details

• Entrez Gene ID: 9126
• Gene Name: structural maintenance of chromosomes 3
• Gene Aliases: BAM, BMH, CDLS3, CSPG6, HCAP, SMC3L1
• Location: Chr.10:110567691-110604634 on Build GRCh38
• Assay Gene Location: Within Exon 11

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SMC3	NM_005445.3	11	991	NP_005436.1
	AF020043.1	11	956	AAC14893.1
	AK289771.1	11	987
	AK315845.1	11	990
	BC047324.1	11	886	AAH47324.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv526452	Chr.10:110503272 - 110659020 on Build GRCh38	Gain	RBM20 SMC3 DUSP5
nsv1054449	Chr.10:110521913 - 110599006 on Build GRCh38	Gain	SMC3
nsv508607	Chr.10:110571773 - 110655342 on Build GRCh38	Deletion	RBM20 SMC3

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

regulation of DNA replication
DNA repair
mitotic spindle organization
sister chromatid cohesion
mitotic sister chromatid cohesion
mitotic nuclear division
meiotic nuclear division
signal transduction
protein sumoylation
stem cell population maintenance
negative regulation of DNA endoreduplication
cell division

Function(s)

chromatin binding
microtubule motor activity
protein binding
ATP binding
mediator complex binding
dynein binding
protein heterodimerization activity