Hs02391820_cn

• Gene Symbol: MEA1
• Assay Reference Genome Location: Chr.6:43007000 on build GRCh38
• Cytoband: 6p21.1

Target Gene Details

• Entrez Gene ID: 4201
• Gene Name: male-enhanced antigen 1
• Gene Aliases: HYS, MEA
• Location: Chr.6:42980344-43016886 on Build GRCh38
• Assay Gene Location: Within Intron 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MEA1	XM_017010868.1			XP_016866357.1
	AK309759.1

Target Gene Details

• Entrez Gene ID: 5528
• Gene Name: protein phosphatase 2 regulatory subunit B'delta
• Gene Aliases: B56D, MRD35
• Location: Chr.6:42984499-43012345 on Build GRCh38
• Assay Gene Location: Within Exon 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PPP2R5D	NM_001270476.1	4	608	NP_001257405.1
	NM_006245.3	4	591	NP_006236.1
	NM_180976.2	4	495	NP_851307.1
	NM_180977.2	2	273	NP_851308.1
	AB000634.1	4	426	BAA20381.1
	AB000635.1	2	120	BAA20382.1
	AB209861.1	2	170	BAD93098.1
	AB451342.1	4	412
	AB451357.1	4	412
	AK122701.1	4	485
	AK290604.1	4	404
	AK291797.1	4	499
	AK299696.1	4	464
	BC001095.2	4	475	AAH01095.1
	BC001175.1	4	402	AAH01175.1
	BC010692.1	4	485	AAH10692.1
	D78360.1	4	393	BAA11372.1
	DA388594.1
	L76702.1	4	599	AAB69751.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3576145	Chr.6:42728097 - 43012090 on Build GRCh38	Gain	RPL7L1 C6orf226 ATP6V0CP3 CNPY3-GNMT GLTSCR1L MEA1 GNMT CNPY3 TBCC PEX6 LOC401261 PPP2R5D PTCRA
nsv602992	Chr.6:42948182 - 43110718 on Build GRCh38	Loss	MRPL2 MEA1 KLC4 GNMT PEX6 RRP36 KLHDC3 CUL7 PPP2R5D CNPY3-GNMT PTK7
nsv1017398	Chr.6:42659705 - 43400998 on Build GRCh38	Gain	ZNF318 ATP6V0CP3 GLTSCR1L CNPY3 TBCC RRP36 LOC401261 PPP2R5D DNPH1 PRPH2 RPL7L1 MRPL2 KLC4 C6orf226 CUL9 SRF UBR2 CNPY3-GNMT MEA1 GNMT TTBK1 PEX6 KLHDC3 CUL7 CRIP3 SLC22A7 PTCRA PTK7
dgv10640n54	Chr.6:43002769 - 43128461 on Build GRCh38	Loss	MRPL2 MEA1 KLC4 RRP36 KLHDC3 CUL7 PPP2R5D PTK7

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protein phosphatase

Gene Ontology Categories:

Process(es)

spermatogenesis
male gonad development
cell differentiation
protein dephosphorylation
signal transduction
nervous system development
regulation of protein phosphatase type 2A activity

Function(s)

protein binding
protein serine/threonine phosphatase activity
protein phosphatase type 2A regulator activity