Hs01827482_cn

• Gene Symbol: CD300A
• Assay Reference Genome Location: Chr.17:74484036 on build GRCh38
• Cytoband: 17q25.1

Target Gene Details

• Entrez Gene ID: 11314
• Gene Name: CD300a molecule
• Gene Aliases: CLM-8, CMRF-35-H9, CMRF-35H, CMRF35-H, CMRF35-H9, CMRF35H, CMRF35H9, IGSF12, IRC1, IRC1/IRC2, IRC2, IRp60
• Location: Chr.17:74466320-74484798 on Build GRCh38
• Assay Gene Location: Within Exon 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CD300A	NM_001256841.1	6	792	NP_001243770.1
	NM_007261.3	7	1131	NP_009192.2
	XM_005256990.2	6	1044	XP_005257047.1
	XM_005256991.4	5	1008	XP_005257048.1
	XM_005256992.4	7	1060	XP_005257049.1
	XM_006721656.3	7	1168	XP_006721719.1
	XM_011524254.2	5	747	XP_011522556.1
	AF020314.1	7	896	AAD01646.1
	AF161346.1	5	408	AAF28906.1
	AJ010101.1	7	839	CAB52291.1
	AJ010102.1	6	500	CAB52292.1
	AJ010103.1	4	251	CAB52293.1
	AJ224864.1	7	1112	CAB55347.1
	AJ238323.1	7	839	CAB66145.1
	AK309631.1	8	1196
	AK309636.1	6	1237
	BC032352.1	7	1096	AAH32352.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv12e196	Chr.17:73675043 - 74565539 on Build GRCh38	Duplication	RPL38 TTYH2 KIF19 DNAI2 BTBD17 GPR142 MGC16275 GPRC5C LOC100130520 CD300A CD300C LINC00469 LOC100134391 CD300LB LOC400620
nsv470600	Chr.17:74466882 - 74550979 on Build GRCh38	Loss	CD300A CD300C CD300LB
esv2761978	Chr.17:73835799 - 74684915 on Build GRCh38	Gain	RPL38 TTYH2 KIF19 DNAI2 BTBD17 RAB37 CD300E LOC101928343 GPR142 CD300LD MGC16275 GPRC5C LOC100130520 C17orf77 CD300A CD300C CD300LB
esv3641230	Chr.17:73831787 - 74694861 on Build GRCh38	Gain	RPL38 CD300LF TTYH2 KIF19 DNAI2 BTBD17 RAB37 CD300E LOC101928343 GPR142 CD300LD MGC16275 GPRC5C LOC100130520 C17orf77 CD300A CD300C CD300LB
dgv3282n100	Chr.17:73814343 - 74719597 on Build GRCh38	Gain	RPL38 CD300LF TTYH2 KIF19 DNAI2 BTBD17 RAB37 CD300E LOC101928343 GPR142 CD300LD MGC16275 GPRC5C LOC100130520 C17orf77 CD300A CD300C LINC00469 CD300LB
esv33995	Chr.17:74261053 - 74732093 on Build GRCh38	Loss	CD300LF TTYH2 KIF19 DNAI2 BTBD17 RAB37 CD300E LOC101928343 GPR142 CD300LD GPRC5C LOC100130520 C17orf77 CD300A CD300C CD300LB
nsv517569	Chr.17:73837862 - 74685802 on Build GRCh38	Gain+Loss	RPL38 TTYH2 KIF19 DNAI2 BTBD17 RAB37 CD300E LOC101928343 GPR142 CD300LD MGC16275 GPRC5C LOC100130520 C17orf77 CD300A CD300C CD300LB
dgv5768n54	Chr.17:73826016 - 74706775 on Build GRCh38	Gain	RPL38 CD300LF TTYH2 KIF19 DNAI2 BTBD17 RAB37 CD300E LOC101928343 GPR142 CD300LD MGC16275 GPRC5C LOC100130520 C17orf77 CD300A CD300C LINC00469 CD300LB
esv3573820	Chr.17:73817932 - 74694378 on Build GRCh38	Gain	RPL38 CD300LF TTYH2 KIF19 DNAI2 BTBD17 RAB37 CD300E LOC101928343 GPR142 CD300LD MGC16275 GPRC5C LOC100130520 C17orf77 CD300A CD300C LINC00469 CD300LB
dgv5774n54	Chr.17:74428381 - 74673021 on Build GRCh38	Gain	CD300LD GPRC5C LOC100130520 C17orf77 CD300A CD300C RAB37 CD300E LOC101928343 CD300LB

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

immunoglobulin receptor superfamily

Gene Ontology Categories:

Process(es)

immune system process
cell adhesion
signal transduction
negative regulation of B cell proliferation
positive regulation of phosphoprotein phosphatase activity
negative regulation of mast cell activation involved in immune response
negative regulation of mast cell degranulation
negative regulation of MAP kinase activity
negative regulation of fibroblast proliferation
regulation of immune response
regulation of T cell receptor signaling pathway
negative regulation of B cell receptor signaling pathway
negative regulation of NK T cell activation
negative regulation of phagocytosis, engulfment
negative regulation of neutrophil activation
negative regulation of eosinophil activation
negative regulation of activation of JAK2 kinase activity
negative regulation of eosinophil migration

Function(s)

phosphatidylserine binding
protein binding
phosphatidylethanolamine binding
signaling receptor activity