Hs01619777_cn

• Gene Symbol: CDT1
• Assay Reference Genome Location: Chr.16:88807472 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 81620
• Gene Name: chromatin licensing and DNA replication factor 1
• Gene Aliases: DUP, RIS2
• Location: Chr.16:88803778-88809258 on Build GRCh38
• Assay Gene Location: Overlaps Exon 9 - Intron 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CDT1	NM_030928.3			NP_112190.2
	AB053172.1			BAB61878.1
	AF070552.1
	AF321125.1			AAG45181.1
	BC000137.2			AAH00137.2
	BC008676.1			AAH08676.1
	BC008860.2			AAH08860.2
	BC009410.1			AAH09410.1
	BC014202.2			AAH14202.2
	BC021126.1
	BC049205.1			AAH49205.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1063024	Chr.16:88707330 - 89238482 on Build GRCh38	Gain	LOC339059 CTU2 CBFA2T3 SLC22A31 PABPN1L LINC00304 APRT PIEZO1 LOC101927793 ACSF3 LOC100289580 CDH15 LOC105371409 GALNS LOC400558 ZNF778 CDT1 LOC107987238 LOC100129697 TRAPPC2L MIR4722
nsv471115	Chr.16:88801844 - 89197442 on Build GRCh38	Loss	CBFA2T3 SLC22A31 PABPN1L LINC00304 APRT LOC101927793 ACSF3 CDH15 LOC105371409 GALNS LOC400558 CDT1 LOC107987238 LOC100129697 TRAPPC2L
dgv3064n100	Chr.16:88683753 - 88846491 on Build GRCh38	Gain	SNAI3-AS1 CDT1 LOC339059 LOC107987238 CTU2 APRT SNAI3 PIEZO1 LOC100289580 RNF166 GALNS MIR4722
nsv573674	Chr.16:88738775 - 89325907 on Build GRCh38	Gain	LOC105371414 LOC339059 CBFA2T3 SLC22A31 PABPN1L LINC00304 APRT PIEZO1 LOC101927793 ACSF3 LOC100289580 CDH15 LOC105371409 GALNS LOC400558 ANKRD11 ZNF778 LOC100287036 CDT1 LOC107987238 LOC100129697 TRAPPC2L
nsv471117	Chr.16:88805821 - 88838392 on Build GRCh38	Gain	CDT1 LOC107987238 APRT GALNS
nsv952071	Chr.16:88790893 - 89019992 on Build GRCh38	Deletion	CDT1 LOC107987238 CBFA2T3 PABPN1L APRT LOC100129697 TRAPPC2L LOC101927793 LOC105371409 GALNS
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	LOC105371414 TUBB3 URAHP CTU2 CBFA2T3 PIEZO1 CDH15 GALNS CYBA FAM157C GAS8-AS1 LOC105371419 SPATA33 CHMP1A IL17C MIR4722 SPATA2L VPS9D1-AS1 CDK10 PABPN1L LINC00304 LOC100289580 LOC105371409 ANKRD11 ZNF778 CPNE7 LOC100287036 PRDM7 GAS8 LOC107987238 MC1R TUBB8P7 LOC100129697 DPEP1 VPS9D1 LOC107984817 AFG3L1P SPIRE2 SLC22A31 APRT SNAI3 LOC101927793 CDT1 DEF8 SPG7 MVD TRAPPC2L ZNF276 RPL13 LOC339059 ACSF3 SNORD68 RNF166 SNAI3-AS1 LOC400558 DBNDD1 CENPBD1 FANCA LOC101927817 TCF25
nsv1063441	Chr.16:88767066 - 88861882 on Build GRCh38	Loss	CDT1 LOC107987238 APRT TRAPPC2L PIEZO1 GALNS
dgv37n68	Chr.16:88767460 - 88944903 on Build GRCh38	Loss	CDT1 LOC107987238 CBFA2T3 PABPN1L APRT LOC100129697 TRAPPC2L PIEZO1 LOC101927793 LOC105371409 GALNS
nsv573718	Chr.16:88807259 - 88810716 on Build GRCh38	Loss	CDT1 APRT
dgv5319n54	Chr.16:88804814 - 88809520 on Build GRCh38	Loss	CDT1 APRT
esv3639555	Chr.16:88745961 - 88899576 on Build GRCh38	Gain	CDT1 LOC107987238 CBFA2T3 PABPN1L APRT TRAPPC2L PIEZO1 LOC101927793 GALNS
nsv573712	Chr.16:88796728 - 88809084 on Build GRCh38	Loss	CDT1
dgv3065n100	Chr.16:88711587 - 88927172 on Build GRCh38	Gain	LOC339059 CTU2 CBFA2T3 PABPN1L APRT PIEZO1 LOC101927793 LOC100289580 GALNS CDT1 LOC107987238 TRAPPC2L MIR4722

More Information

Additional Information:

For this assay, SNP(s) [rs115396767] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Process(es)

DNA replication checkpoint
G1/S transition of mitotic cell cycle
regulation of transcription involved in G1/S transition of mitotic cell cycle
DNA replication
regulation of DNA-dependent DNA replication initiation
regulation of nuclear cell cycle DNA replication

Function(s)

DNA binding
protein binding