Hs01354437_cn

• Gene Symbol: SEMA4C
• Assay Reference Genome Location: Chr.2:96865078 on build GRCh38
• Cytoband: 2q11.2

Target Gene Details

• Entrez Gene ID: 54910
• Gene Name: semaphorin 4C
• Gene Aliases: M-SEMA-F, SEMACL1, SEMAF, SEMAI
• Location: Chr.2:96859736-96870943 on Build GRCh38
• Assay Gene Location: Overlaps Intron 9 - Exon 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SEMA4C	NM_017789.4			NP_060259.4
	XM_006712606.3			XP_006712669.2
	XM_011511378.2			XP_011509680.1
	XM_011511379.2			XP_011509681.1
	XM_011511380.1			XP_011509682.1
	XM_011511381.1			XP_011509683.1
	XM_011511382.2			XP_011509684.1
	XM_011511383.1			XP_011509685.1
	XM_017004393.1			XP_016859882.1
	XM_017004394.1			XP_016859883.1
	AB051526.1			BAB21830.1
	AY358842.1			AAQ89201.1
	BC017476.1			AAH17476.2
	BC109103.1			AAI09104.1
	BC109104.1			AAI09105.1
	BI518922.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv526313	Chr.2:96667755 - 96994882 on Build GRCh38	Loss	MIR3127 ANKRD39 CNNM4 SEMA4C LOC101927053 ANKRD23 LMAN2L FER1L5 FAM178B CNNM3
dgv607e201	Chr.2:95855884 - 97561622 on Build GRCh38	Deletion	MIR3127 FAHD2B STARD7-AS1 LOC101927053 ANKRD36C FAM178B SNRNP200 LOC105373495 DUSP2 ADRA2B ARID5A LOC107984110 CNNM3 LOC105373496 GPAT2 ANKRD36 ANKRD39 ASTL FAHD2CP CIAO1 SEMA4C LOC100506076 STARD7 FER1L5 ITPRIPL1 NCAPH TMEM127 LOC100506123 KANSL3 CNNM4 LOC653924 ANKRD23 LMAN2L ANKRD36B NEURL3
nsv1135873	Chr.2:95981454 - 97579645 on Build GRCh38	Deletion	MIR3127 FAHD2B STARD7-AS1 LOC101927053 ANKRD36C FAM178B SNRNP200 LOC105373495 DUSP2 ADRA2B ARID5A LOC107984110 CNNM3 LOC105373496 GPAT2 ANKRD36 ANKRD39 ASTL FAHD2CP CIAO1 SEMA4C LOC100506076 STARD7 FER1L5 ITPRIPL1 NCAPH TMEM127 LOC100506123 KANSL3 CNNM4 LOC653924 ANKRD23 LMAN2L ANKRD36B NEURL3
esv3425717	Chr.2:95859900 - 97515905 on Build GRCh38	Duplication	MIR3127 FAHD2B STARD7-AS1 LOC101927053 ANKRD36C FAM178B SNRNP200 LOC105373495 DUSP2 ADRA2B ARID5A LOC107984110 CNNM3 LOC105373496 GPAT2 ANKRD36 ANKRD39 ASTL FAHD2CP CIAO1 SEMA4C LOC100506076 STARD7 FER1L5 ITPRIPL1 NCAPH TMEM127 LOC100506123 KANSL3 CNNM4 LOC653924 ANKRD23 LMAN2L ANKRD36B NEURL3

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

membrane-bound signaling molecule, intercellular signal molecule

Gene Ontology Categories:

Process(es)

neural crest cell migration
neural tube closure
cell migration in hindbrain
cerebellum development
positive regulation of cell migration
positive regulation of stress-activated MAPK cascade
muscle cell differentiation
negative regulation of axon extension involved in axon guidance
negative chemotaxis
semaphorin-plexin signaling pathway

Function(s)

protein binding
semaphorin receptor binding
neuropilin binding
chemorepellent activity