Hs01209100_cn

• Gene Symbol: CTNNA3
• Assay Reference Genome Location: Chr.10:67097766 on build GRCh38
• Cytoband: 10q21.3

Target Gene Details

• Entrez Gene ID: 29119
• Gene Name: catenin alpha 3
• Gene Aliases: ARVD13, VR22
• Location: Chr.10:65912518-67696217 on Build GRCh38
• Assay Gene Location: Within Intron 14

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CTNNA3	NM_001127384.2			NP_001120856.1
	NM_013266.3			NP_037398.2
	XM_017016151.1			XP_016871640.1
	XM_017016152.1			XP_016871641.1
	XM_017016153.1			XP_016871642.1
	XM_017016154.1			XP_016871643.1
	XM_017016155.1			XP_016871644.1
	XM_017016156.1			XP_016871645.1
	AF091606.1			AAF21801.1
	AK289756.1
	AK308726.1
	AK313882.1
	BC065819.1			AAH65819.1

Target Gene Details

• Entrez Gene ID: 347731
• Gene Name: leucine rich repeat transmembrane neuronal 3
• Gene Aliases: -
• Location: Chr.10:66926034-67101551 on Build GRCh38
• Assay Gene Location: Within Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LRRTM3	NM_178011.4	3	2266	NP_821079.3
	NR_111909.1	3	310
	AK290168.1	3	1799
	AK294029.1	2	486
	BC111492.1	3	2218	AAI11493.1
	BC113715.1
	BC113717.1	3	1776
	BU154601.1	3	293
	BX640611.1	3	2245	CAE45717.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv520745	Chr.10:66982077 - 67162484 on Build GRCh38	Gain	CTNNA3 LRRTM3 LOC101928961
dgv916n100	Chr.10:66975498 - 67173658 on Build GRCh38	Gain	CTNNA3 LRRTM3 LOC101928961
dgv33e55	Chr.10:66929809 - 67178536 on Build GRCh38	Gain	CTNNA3 LRRTM3 LOC101928961
nsv831905	Chr.10:67096507 - 67239655 on Build GRCh38	Gain	CTNNA3 LRRTM3

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-motor actin binding protein, transmembrane signal receptor

Gene Ontology Categories:

Process(es)

single organismal cell-cell adhesion
bundle of His cell-Purkinje myocyte adhesion involved in cell communication
regulation of heart rate by cardiac conduction
regulation of ventricular cardiac muscle cell action potential
negative regulation of protein kinase activity
cytokine-mediated signaling pathway
negative regulation of JAK-STAT cascade
positive regulation of synapse assembly
positive regulation of beta-amyloid formation

Function(s)

protein binding
beta-catenin binding
cadherin binding
actin filament binding
cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication
protein kinase inhibitor activity