Hs01197622_cn

• Gene Symbol: DGKQ
• Assay Reference Genome Location: Chr.4:967141 on build GRCh38
• Cytoband: 4p16.3

Target Gene Details

• Entrez Gene ID: 1609
• Gene Name: diacylglycerol kinase theta
• Gene Aliases: DAGK, DAGK4, DAGK7
• Location: Chr.4:958884-973560 on Build GRCh38
• Assay Gene Location: Overlaps Intron 9 - Exon 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DGKQ	NM_001347.3			NP_001338.2
	XM_011513411.1			XP_011511713.1
	XM_011513412.1			XP_011511714.1
	XM_011513414.2			XP_011511716.1
	XM_011513415.1			XP_011511717.1
	XM_017007814.1			XP_016863303.1
	XM_017007815.1			XP_016863304.1
	AB209503.1			BAD92740.1
	BC063801.1			AAH63801.1
	GU727647.1
	L38707.1			AAA98749.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1003219	Chr.4:776106 - 1111676 on Build GRCh38	Gain	RNF212 GAK TMEM175 DGKQ LOC100129917 FGFRL1 SLC26A1 CPLX1 IDUA
nsv593226	Chr.4:948218 - 1025223 on Build GRCh38	Loss	TMEM175 DGKQ FGFRL1 SLC26A1 IDUA
nsv4196	Chr.4:961755 - 1004599 on Build GRCh38	Deletion	DGKQ SLC26A1 IDUA
nsv822425	Chr.4:546316 - 1420011 on Build GRCh38	Loss	NKX1-1 CTBP1 UVSSA SPON2 LOC107986211 SLC26A1 CPLX1 RNF212 MFSD7 LOC100130872 CTBP1-AS LOC105374344 DGKQ MAEA LOC100129917 FGFRL1 PDE6B GAK ATP5I CRIPAK MYL5 LOC101928548 TMEM175 PCGF3 TMED11P IDUA LOC101928521 CTBP1-AS2
nsv950327	Chr.4:945913 - 978512 on Build GRCh38	Deletion	TMEM175 DGKQ
dgv5079n100	Chr.4:843485 - 970603 on Build GRCh38	Gain	GAK TMEM175 DGKQ
esv29984	Chr.4:857569 - 970571 on Build GRCh38	Loss	GAK TMEM175 DGKQ
nsv469998	Chr.4:815805 - 1093743 on Build GRCh38	Loss	RNF212 GAK TMEM175 DGKQ FGFRL1 SLC26A1 CPLX1 IDUA
nsv1008352	Chr.4:819605 - 1041628 on Build GRCh38	Gain	GAK TMEM175 DGKQ FGFRL1 SLC26A1 CPLX1 IDUA

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

kinase

Gene Ontology Categories:

Process(es)

regulation of transcription from RNA polymerase II promoter
G-protein coupled receptor signaling pathway
protein kinase C-activating G-protein coupled receptor signaling pathway
phosphorylation
cAMP-mediated signaling
platelet activation
response to ATP
thrombin receptor signaling pathway
protein kinase C signaling

Function(s)

diacylglycerol kinase activity
protein binding
ATP binding
kinase binding
activating transcription factor binding
phospholipase binding
metal ion binding