Hs01089196_cn

• Gene Symbol: KLC3
• Assay Reference Genome Location: Chr.19:45349464 on build GRCh38
• Cytoband: 19q13.32

Target Gene Details

• Entrez Gene ID: 147700
• Gene Name: kinesin light chain 3
• Gene Aliases: KLC2, KLC2L, KLCt, KNS2B
• Location: Chr.19:45340740-45351520 on Build GRCh38
• Assay Gene Location: Within Exon 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
KLC3	NM_177417.2	8	1120	NP_803136.2
	AK092481.1	7	1147	BAC03901.1
	BC062998.1	8	1107
	BC073841.1	8	1096	AAH73841.1
	BC126418.1	7	1136
	BC133037.1	7	1136

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833845	Chr.19:45308814 - 45457371 on Build GRCh38	Loss	KLC3 CKM CD3EAP MIR6088 PPP1R13L ERCC2 ERCC1
dgv29n64	Chr.19:45334011 - 45373709 on Build GRCh38	Gain	KLC3 ERCC2
esv3644502	Chr.19:45323147 - 45403933 on Build GRCh38	Gain	KLC3 PPP1R13L ERCC2
dgv1054e212	Chr.19:45347119 - 45407663 on Build GRCh38	Gain	KLC3 CD3EAP PPP1R13L ERCC2 ERCC1
esv3644504	Chr.19:45342675 - 45373732 on Build GRCh38	Gain	KLC3 ERCC2
nsv458711	Chr.19:45323108 - 45408744 on Build GRCh38	Gain	KLC3 CD3EAP PPP1R13L ERCC2 ERCC1
nsv1063547	Chr.19:45322368 - 45400204 on Build GRCh38	Gain	KLC3 CKM PPP1R13L ERCC2
dgv3606n100	Chr.19:45347435 - 45400204 on Build GRCh38	Gain	KLC3 PPP1R13L ERCC2
nsv833844	Chr.19:45181051 - 45384148 on Build GRCh38	Loss	KLC3 CKM BLOC1S3 EXOC3L2 MARK4 PPP1R13L ERCC2
nsv1160648	Chr.19:45347447 - 45368176 on Build GRCh38	Duplication	KLC3 ERCC2
nsv579868	Chr.19:45334025 - 45359625 on Build GRCh38	Gain	KLC3 ERCC2

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

cytoskeletal protein, microtubule binding motor protein, microtubule or microtubule-binding cytoskeletal protein

Gene Ontology Categories:

Process(es)

axo-dendritic transport

Function(s)

microtubule motor activity
protein binding
microtubule binding
kinesin binding