Hs00784278_cn

• Gene Symbol: LONP1
• Assay Reference Genome Location: Chr.19:5691872 on build GRCh38
• Cytoband: 19p13.3

Target Gene Details

• Entrez Gene ID: 9361
• Gene Name: lon peptidase 1, mitochondrial
• Gene Aliases: CODASS, LON, LONP, LonHS, PIM1, PRSS15, hLON
• Location: Chr.19:5691834-5720452 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 19

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LONP1	NM_001276479.1			NP_001263408.1
	NM_001276480.1			NP_001263409.1
	NM_004793.3			NP_004784.2
	NR_076392.1
	AK056366.1
	AK096433.1
	AK096626.1			BAC04829.1
	AK127867.1
	AK298531.1
	AK309720.1
	AL096720.1
	BC000235.1			AAH00235.1
	U02389.1			AAA61616.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv953952	Chr.19:5645090 - 5708389 on Build GRCh38	Deletion	LOC107985320 RPL36 C19orf70 HSD11B1L SAFB LONP1
nsv1062851	Chr.19:5531540 - 5893590 on Build GRCh38	Gain	DUS3L RPL36 LOC101928844 FUT5 CATSPERD NRTN LOC107985320 TINCR NDUFA11 C19orf70 HSD11B1L PRR22 FUT6 SAFB2 SAFB LONP1 FUT3

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

serine protease

Gene Ontology Categories:

Process(es)

mitochondrial genome maintenance
response to hypoxia
misfolded or incompletely synthesized protein catabolic process
mitochondrion organization
aging
response to hormone
response to aluminum ion
mitochondrial DNA metabolic process
cellular response to oxidative stress
chaperone-mediated protein complex assembly
protein homooligomerization
proteolysis involved in cellular protein catabolic process
oxidation-dependent protein catabolic process
regulation of mitochondrial DNA replication

Function(s)

single-stranded DNA binding
single-stranded RNA binding
ATP-dependent peptidase activity
serine-type endopeptidase activity
protein binding
ATP binding
ADP binding
sequence-specific DNA binding
G-quadruplex DNA binding
DNA polymerase binding
mitochondrial light strand promoter anti-sense binding
mitochondrial heavy strand promoter anti-sense binding
mitochondrial light strand promoter sense binding
mitochondrial heavy strand promoter sense binding