Hs00754877_cn

• Gene Symbol: SETD7
• Assay Reference Genome Location: Chr.4:139508193 on build GRCh38
• Cytoband: 4q31.1

Target Gene Details

• Entrez Gene ID: 80854
• Gene Name: SET domain containing lysine methyltransferase 7
• Gene Aliases: KMT7, SET7, SET7/9, SET9
• Location: Chr.4:139495934-139556769 on Build GRCh38
• Assay Gene Location: Within Exon 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SETD7	NM_001306199.1			NP_001293128.1
	NM_030648.3	8	5203	NP_085151.1
	XM_017008661.1	6	4296	XP_016864150.1
	AB051504.1	8	4838
	AK310856.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3894040	Chr.4:139499096 - 139522362 on Build GRCh38	Loss	SETD7
nsv830085	Chr.4:139393507 - 139586168 on Build GRCh38	Loss	LOC101927451 SETD7 RAB33B LOC105377450
nsv830086	Chr.4:139494751 - 139671217 on Build GRCh38	Gain	MGST2 LOC101927490 LOC105377622 SETD7

More Information

Additional Information:

For this assay, SNP(s) [rs114397080] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

chromatin/chromatin-binding, or -regulatory protein, histone modifying enzyme

Gene Ontology Categories:

Process(es)

transcription, DNA-templated
cellular response to DNA damage stimulus
chromatin modification
peptidyl-lysine monomethylation
peptidyl-lysine dimethylation
histone lysine methylation
response to ethanol
positive regulation of transcription, DNA-templated
regulation of histone H3-K9 methylation
heterochromatin organization

Function(s)

p53 binding
chromatin binding
protein binding
protein-lysine N-methyltransferase activity
histone-lysine N-methyltransferase activity