Hs00646712_cn

• Gene Symbol: SYTL2
• Assay Reference Genome Location: Chr.11:85709412 on build GRCh38
• Cytoband: 11q14.1

Target Gene Details

• Entrez Gene ID: 54843
• Gene Name: synaptotagmin like 2
• Gene Aliases: CHR11SYT, EXO4, PPP1R151, SGA72M, SLP2, SLP2A
• Location: Chr.11:85694221-85811182 on Build GRCh38
• Assay Gene Location: Within Exon 14

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SYTL2	NM_001162951.2	12	2263	NP_001156423.1
	NM_001162952.2	4	793	NP_001156424.1
	NM_001162953.2	12	2266	NP_001156425.1
	NM_001289608.1	13	2072	NP_001276537.1
	NM_001289609.1	4	793	NP_001276538.1
	NM_001289610.1	5	477	NP_001276539.1
	NM_032943.4	13	2442	NP_116561.1
	NM_206929.3	6	597	NP_996812.1
	NM_206930.3	3	770	NP_996813.1
	XM_005274057.1	12	5902	XP_005274114.1
	XM_005274060.1	13	2086	XP_005274117.1
	XM_005274061.1	13	2083	XP_005274118.1
	XM_005274062.2	14	2507	XP_005274119.1
	XM_005274063.1	12	1966	XP_005274120.1
	XM_005274066.1	11	1915	XP_005274123.1
	XM_005274067.4	5	2209	XP_005274124.1
	XM_011545105.1	13	5950	XP_011543407.1
	XM_011545106.1	13	5947	XP_011543408.1
	XM_011545107.2	14	6371	XP_011543409.1
	XM_011545108.1	12	5830	XP_011543410.1
	XM_011545109.2	13	5932	XP_011543411.1
	XM_011545110.1	13	5950	XP_011543412.1
	XM_011545114.2	4	2115	XP_011543416.1
	XM_011545115.1	2	209	XP_011543417.1
	XM_011545116.2	3	1994	XP_011543418.1
	XM_017017933.1	12	5899	XP_016873422.1
	XM_017017934.1	14	6368	XP_016873423.1
	XM_017017935.1	10	5746	XP_016873424.1
	XM_017017936.1	10	5444	XP_016873425.1
	XM_017017937.1	13	1987	XP_016873426.1
	XM_017017938.1	12	1945	XP_016873427.1
	XM_017017939.1	6	2253	XP_016873428.1
	XM_017017940.1	5	2205	XP_016873429.1
	AB046817.1	13	2453	BAB13423.1
	AJ303364.1	1	89	CAC33886.1
	AK024872.1	3	934	BAB15030.1
	AK074737.1	6	554	BAC11170.1
	AK092121.1	3	588
	AK124754.1	6	2178	BAC85937.1
	AK127504.1	7	3141	BAC87010.1
	AK131365.1	6	1070	BAD18516.1
	AK222707.1	3	934
	AK222710.1	3	934
	AK296224.1	13	2054
	AK296740.1	10	2002
	AK298604.1	5	395
	AL601023.1	5	450
	AY386362.1	6	4457	AAR25619.1
	BC015540.2	3	264
	BC110315.1	4	322	AAI10316.1
	BC136450.1	12	2198
	BC144114.1	12	2198
	BC144115.1	12	2195
	BX647671.1	7	2893
	BX648068.1	6	2339
	CB046277.1	6	554
	DA378461.1
	EU035829.1	12	1919

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv832222	Chr.11:85694669 - 85892938 on Build GRCh38	Gain	CCDC83 SYTL2
nsv468768	Chr.11:85684137 - 85725309 on Build GRCh38	Loss	SYTL2 CCDC89
esv2759845	Chr.11:85469436 - 85892945 on Build GRCh38	Gain+Loss	TMEM126A DLG2 CCDC83 SYTL2 CCDC89 TMEM126B CREBZF

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

intracellular protein transport
exocytosis
vesicle docking involved in exocytosis
vesicle fusion
negative regulation of phosphatase activity
vesicle-mediated transport
regulation of calcium ion-dependent exocytosis
calcium ion-regulated exocytosis of neurotransmitter
positive regulation of mucus secretion
protein localization to plasma membrane

Function(s)

phosphatidylserine binding
calcium ion binding
protein binding
calcium-dependent phospholipid binding
phosphatidylinositol-4,5-bisphosphate binding
Rab GTPase binding
phosphatase binding
syntaxin binding
clathrin binding
neurexin family protein binding