Hs00236886_cn

• Gene Symbol: CDT1
• Assay Reference Genome Location: Chr.16:88805534 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 81620
• Gene Name: chromatin licensing and DNA replication factor 1
• Gene Aliases: DUP, RIS2
• Location: Chr.16:88803778-88809258 on Build GRCh38
• Assay Gene Location: Within Exon 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CDT1	NM_030928.3	4	637	NP_112190.2
	AB053172.1	4	637	BAB61878.1
	AF070552.1	2	178
	AF321125.1	4	608	AAG45181.1
	BC000137.2	4	599	AAH00137.2
	BC008676.1	4	475	AAH08676.1
	BC008860.2	4	530	AAH08860.2
	BC009410.1	4	593	AAH09410.1
	BC021126.1	2	169
	BC049205.1	2	241	AAH49205.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv5313n54	Chr.16:88795879 - 88806103 on Build GRCh38	Loss	CDT1
nsv573677	Chr.16:88764428 - 88805821 on Build GRCh38	Loss	CDT1 PIEZO1
nsv1063024	Chr.16:88707330 - 89238482 on Build GRCh38	Gain	CDT1 LOC100289580 PIEZO1 LOC101927793 LOC400558 ZNF778 PABPN1L LOC100129697 ACSF3 CDH15 CTU2 LOC105371409 MIR4722 CBFA2T3 LOC107987238 APRT LOC339059 TRAPPC2L LINC00304 GALNS SLC22A31
nsv471115	Chr.16:88801844 - 89197442 on Build GRCh38	Loss	CDT1 LOC101927793 LOC400558 PABPN1L LOC100129697 ACSF3 CDH15 LOC105371409 CBFA2T3 LOC107987238 APRT TRAPPC2L LINC00304 GALNS SLC22A31
dgv3064n100	Chr.16:88683753 - 88846491 on Build GRCh38	Gain	SNAI3-AS1 CTU2 MIR4722 CDT1 LOC107987238 LOC100289580 PIEZO1 APRT LOC339059 GALNS SNAI3 RNF166
nsv573674	Chr.16:88738775 - 89325907 on Build GRCh38	Gain	CDT1 LOC100289580 PIEZO1 LOC100287036 LOC101927793 LOC105371414 LOC400558 ZNF778 PABPN1L LOC100129697 ACSF3 CDH15 LOC105371409 ANKRD11 CBFA2T3 LOC107987238 APRT LOC339059 TRAPPC2L LINC00304 GALNS SLC22A31
nsv952071	Chr.16:88790893 - 89019992 on Build GRCh38	Deletion	LOC105371409 CDT1 CBFA2T3 LOC107987238 APRT TRAPPC2L LOC101927793 GALNS PABPN1L LOC100129697
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	VPS9D1 GAS8 ZNF778 TCF25 LOC100129697 DPEP1 CBFA2T3 LOC339059 SNORD68 GALNS SPATA33 IL17C MC1R URAHP LOC100289580 LOC101927817 CPNE7 LOC101927793 DBNDD1 PRDM7 PABPN1L LOC107987238 CDK10 APRT TRAPPC2L LOC107984817 AFG3L1P FANCA SNAI3 SLC22A31 SPATA2L PIEZO1 TUBB8P7 LOC105371414 LOC400558 VPS9D1-AS1 TUBB3 CTU2 DEF8 CYBA SPG7 SNAI3-AS1 CDT1 LOC100287036 GAS8-AS1 RPL13 LOC105371419 RNF166 MVD ACSF3 ZNF276 CDH15 CENPBD1 LOC105371409 ANKRD11 MIR4722 FAM157C SPIRE2 CHMP1A LINC00304
nsv1063441	Chr.16:88767066 - 88861882 on Build GRCh38	Loss	CDT1 LOC107987238 PIEZO1 APRT TRAPPC2L GALNS
dgv37n68	Chr.16:88767460 - 88944903 on Build GRCh38	Loss	LOC105371409 CDT1 CBFA2T3 LOC107987238 PIEZO1 APRT TRAPPC2L LOC101927793 GALNS PABPN1L LOC100129697
dgv5319n54	Chr.16:88804814 - 88809520 on Build GRCh38	Loss	CDT1 APRT
esv3639555	Chr.16:88745961 - 88899576 on Build GRCh38	Gain	CDT1 CBFA2T3 LOC107987238 PIEZO1 APRT TRAPPC2L LOC101927793 GALNS PABPN1L
nsv573712	Chr.16:88796728 - 88809084 on Build GRCh38	Loss	CDT1
dgv3065n100	Chr.16:88711587 - 88927172 on Build GRCh38	Gain	CDT1 LOC100289580 PIEZO1 LOC101927793 PABPN1L CTU2 MIR4722 CBFA2T3 LOC107987238 APRT LOC339059 TRAPPC2L GALNS

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Process(es)

DNA replication checkpoint
G1/S transition of mitotic cell cycle
regulation of transcription involved in G1/S transition of mitotic cell cycle
DNA replication
regulation of DNA-dependent DNA replication initiation
regulation of nuclear cell cycle DNA replication

Function(s)

DNA binding
protein binding