Hs00232010_cn

• Gene Symbol: SEMA4C
• Assay Reference Genome Location: Chr.2:96865222 on build GRCh38
• Cytoband: 2q11.2

Target Gene Details

• Entrez Gene ID: 54910
• Gene Name: semaphorin 4C
• Gene Aliases: M-SEMA-F, SEMACL1, SEMAF, SEMAI
• Location: Chr.2:96859736-96870943 on Build GRCh38
• Assay Gene Location: Overlaps Intron 9 - Exon 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SEMA4C	NM_017789.4			NP_060259.4
	XM_006712606.3			XP_006712669.2
	XM_011511378.2			XP_011509680.1
	XM_011511379.2			XP_011509681.1
	XM_011511380.1			XP_011509682.1
	XM_011511381.1			XP_011509683.1
	XM_011511382.2			XP_011509684.1
	XM_011511383.1			XP_011509685.1
	XM_017004393.1			XP_016859882.1
	XM_017004394.1			XP_016859883.1
	AB051526.1			BAB21830.1
	AY358842.1			AAQ89201.1
	BC017476.1			AAH17476.2
	BC109103.1			AAI09104.1
	BC109104.1			AAI09105.1
	BI518922.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv526313	Chr.2:96667755 - 96994882 on Build GRCh38	Loss	SEMA4C ANKRD39 MIR3127 FAM178B CNNM3 ANKRD23 FER1L5 LMAN2L LOC101927053 CNNM4
dgv607e201	Chr.2:95855884 - 97561622 on Build GRCh38	Deletion	LOC100506123 ANKRD39 SNRNP200 ITPRIPL1 LOC105373495 LOC105373496 STARD7-AS1 LOC100506076 KANSL3 GPAT2 SEMA4C MIR3127 ANKRD36B FER1L5 LOC653924 FAHD2CP FAHD2B ANKRD36C STARD7 NCAPH LMAN2L LOC107984110 FAM178B ANKRD23 CIAO1 ANKRD36 CNNM4 NEURL3 ARID5A ASTL CNNM3 ADRA2B DUSP2 TMEM127 LOC101927053
nsv1135873	Chr.2:95981454 - 97579645 on Build GRCh38	Deletion	LOC100506123 ANKRD39 SNRNP200 ITPRIPL1 LOC105373495 LOC105373496 STARD7-AS1 LOC100506076 KANSL3 GPAT2 SEMA4C MIR3127 ANKRD36B FER1L5 LOC653924 FAHD2CP FAHD2B ANKRD36C STARD7 NCAPH LMAN2L LOC107984110 FAM178B ANKRD23 CIAO1 ANKRD36 CNNM4 NEURL3 ARID5A ASTL CNNM3 ADRA2B DUSP2 TMEM127 LOC101927053
esv3425717	Chr.2:95859900 - 97515905 on Build GRCh38	Duplication	LOC100506123 ANKRD39 SNRNP200 ITPRIPL1 LOC105373495 LOC105373496 STARD7-AS1 LOC100506076 KANSL3 GPAT2 SEMA4C MIR3127 ANKRD36B FER1L5 LOC653924 FAHD2CP FAHD2B ANKRD36C STARD7 NCAPH LMAN2L LOC107984110 FAM178B ANKRD23 CIAO1 ANKRD36 CNNM4 NEURL3 ARID5A ASTL CNNM3 ADRA2B DUSP2 TMEM127 LOC101927053

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

membrane-bound signaling molecule, intercellular signal molecule

Gene Ontology Categories:

Process(es)

neural crest cell migration
neural tube closure
cell migration in hindbrain
cerebellum development
positive regulation of cell migration
positive regulation of stress-activated MAPK cascade
muscle cell differentiation
negative regulation of axon extension involved in axon guidance
negative chemotaxis
semaphorin-plexin signaling pathway

Function(s)

protein binding
semaphorin receptor binding
neuropilin binding
chemorepellent activity