Invitrogen
Catalog # PA5-50931
Quantity:
TESTED APPLICATIONS | DILUTION |
---|---|
ELISA (ELISA) | 1:40,000 |
Immunohistochemistry (IHC) | 1:100-1:300 |
Western Blot (WB) | 1:500-1:2,000 |
Species reactivity | Human, Mouse, Rat |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | Synthesized peptide derived from human cGKII around the non-phosphorylation site of S126. |
Conjugate | Unconjugated |
Form | Liquid |
Concentration | 1 mg/mL |
Purification | Antigen affinity chromatography |
Storage buffer | PBS, pH 7.4, with 0.5% BSA, 50% glycerol |
Contains | 0.02% sodium azide |
Storage conditions | -20° C, Avoid Freeze/Thaw Cycles |
RRID | AB_2636379 |
cGKII Polyclonal Antibody detects endogenous levels of cGKII protein.
PRKG2 (PKG2, cGKII) exhibits many cellular functions and has cAMP- and cGMP-dependent protein kinase activity. cGKII is thought to play a key role in a diverse set of physiological pathway. cGKII may mediate intestinal secretion of water and electrolytes induced by the E. coli toxin STa and the intestinal peptide guanylin. Identification of the pathway that mediates intestinal fluid secretion by E. coli. cGKII is postulated to be a molecular switch that couples the cessation of proliferation and the start of hypertrophic chondrocyte differentiation through attenuating SOX9 function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CGK 2; cGK2; cGKII; cGMP dependent protein kinase type II; cGMP-dependent protein kinase 2; cGMP-dependent protein kinase II; EC 2.7.11.12; protein kinase cGMP- dependent type 2; protein kinase, cGMP- dependent, type 2; protein kinase, cGMP- dependent, type II; testicular tissue protein Li 99; type II cGMP-dependent protein kinase
Gene Aliases: AW212535; cGK-II; cGK2; CGKII; GDPKII; PRKG2; PRKGR2
UniProt ID: (Human) Q13237, (Rat) Q64595
Entrez Gene ID: (Human) 5593, (Rat) 25523, (Mouse) 19092
Molecular Function:
non-receptor serine/threonine protein kinase
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