Invitrogen
Catalog # PA5-51156
Quantity:
TESTED APPLICATIONS | DILUTION |
---|---|
Immunohistochemistry (Paraffin) (IHC (P)) | 1:100-1:200 |
Western Blot (WB) | 1:200-1:1,000 |
Species reactivity | Human |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | Full length fusion protein of human VDAC3 |
Conjugate | Unconjugated |
Form | Liquid |
Concentration | 0.7 mg/mL |
Purification | Antigen affinity chromatography |
Storage buffer | PBS, pH 7.4, with 40% glycerol |
Contains | 0.05% sodium azide |
Storage conditions | -20°C |
RRID | AB_2636604 |
The antibody detects endogenous levels of total VDAC3 protein.
The Voltage-Dependent Anion Channel (VDAC) of the outer mitochondrial membrane, a small abundant protein found in all eukaryotic kingdoms, forms a voltage-gated pore when incorporated into planar lipid bilayers. VDAC is also the site of binding of the metabolic enzymes hexokinase and glycerol kinase to the mitochondrion in what may be a significant metabolic regulatory interaction. VDAC3 is involved specifically in translocation of adenine nucleotides through the outer membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Outer mitochondrial membrane protein porin 3; VDAC-3; voltage-dependent anion channel 3; Voltage-dependent anion-selective channel protein 3
Gene Aliases: HD-VDAC3; VDAC-3; VDAC3
UniProt ID: (Human) Q9Y277
Entrez Gene ID: (Human) 7419
Molecular Function:
voltage-gated ion channel
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