Invitrogen
Catalog # PA5-50281
Quantity:
TESTED APPLICATIONS | DILUTION |
---|---|
Immunohistochemistry (Paraffin) (IHC (P)) | 1:25-1:100 |
Western Blot (WB) | 1:200-1:1,000 |
Species reactivity | Human |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | Fusion protein corresponding to residues near the C terminal of human Syntaxin binding protein 2 |
Conjugate | Unconjugated |
Form | Liquid |
Concentration | 0.7 mg/mL |
Purification | Antigen affinity chromatography |
Storage buffer | PBS, pH 7.4, with 40% glycerol |
Contains | 0.05% sodium azide |
Storage conditions | -20°C |
RRID | AB_2635734 |
The antibody detects endogenous levels of total STXBP2 protein.
This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Protein unc-18 homolog 2; Protein unc-18 homolog B; Syntaxin-binding protein 2; Unc-18B; Unc18-2
Gene Aliases: FHL5; Hunc18b; MUNC18-2; pp10122; STXBP2; UNC18-2; UNC18B
UniProt ID: (Human) Q15833
Entrez Gene ID: (Human) 6813
Molecular Function:
membrane trafficking regulatory protein
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