Catalog # PA1-46473
Quantity:
TESTED APPLICATIONS | DILUTION |
---|---|
Western Blot (WB) | 2 µg/mL |
Immunocytochemistry (ICC/IF) | 1:50 |
PUBLISHED APPLICATIONS | |
---|---|
Western Blot (WB) | See 1 publications below |
Species reactivity | Mouse, Rat |
Published species | Mouse |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | Synthetic peptide corresponding to residues 1200-1300 of an internal portion of mouse TRPM2. [Swiss-Prot# Q91YD4] |
Conjugate | Unconjugated |
Form | Liquid |
Concentration | 1.5 mg/mL |
Purification | Antigen affinity chromatography |
Storage buffer | PBS with 30% glycerol |
Contains | 0.1% sodium azide |
Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID | AB_2272268 |
Suggested positive control: mouse brain membrane protein.
TRPM2 belongs to the ion transport protein family which includes Sodium, Potassium, Calcium ion channels. This family is characterized by proteins possessing 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. TRPM2 is activated by oxidative stress and confers susceptibility to cell death. Further, TRPM2 is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. Several alternatively spliced transcript variants of the TRPM2 gene have been described, but their full-length nature is not known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: EC 3.6.1.13; EREG 1; KNP 3; Long transient receptor potential channel 2; LTRPC 2; LTrpC-2; MGC133383; null; Transient receptor potential cation channel subfamily M member 2; Transient receptor potential channel 7; transient receptor potential melastatin family 2; transient receptor protein 7; TRPC 7; TrpC7; TRPM 2
Gene Aliases: 9830168K16Rik; C79133; LTRPC2; Trp7; TRPC7; Trpm2; Trpm2-predicted; Trrp7
UniProt ID: (Rat) E9PTA2, (Mouse) Q91YD4
Entrez Gene ID: (Rat) 294329, (Mouse) 28240
Molecular Function:
ion channel
transporter
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