Invitrogen
TESTED APPLICATIONS | DILUTION |
---|---|
Flow Cytometry (Flow) | 1:10-1:50 |
Immunohistochemistry (Paraffin) (IHC (P)) | 1:50-1:100 |
Western Blot (WB) | 1:1,000 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | KLH conjugated synthetic peptide between 243-271 amino acids from the C-terminal region of human RGP1. |
Conjugate | Unconjugated |
Form | Liquid |
Concentration | Lot-Specific |
Storage conditions | -20° C, Avoid Freeze/Thaw Cycles |
RRID | AB_2635058 |
Predicted to react with bovine based on sequence homology.
Retrograde golgi transport homolog 1 (RGP1) is the mammalian homolog to the yeast RGP1, a protein that forms a tight complex with RIC1. This complex binds Ypt6p and stimulates guanine nucleotide exchange. RGP1 is localized to the Golgi and is thought to be a potential Golgi recycling factor. Rgp1 yeast mutants exhibit defects in retrograde trafficking similar to those seen in yeast with mutations in other retrograde Golgi transport proteins. It is expected that RGP1 plays a similar role in mammalian cells to that seen in yeast.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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